Bhushan Bharat, Chen Nianhuan
Nanotribology Laboratory for Information Storage and MEMS/NEMS, NLIM, 650 Ackerman Road, Suite 255, Ohio State University, Columbus, 43210, USA.
Ultramicroscopy. 2006 Jun-Jul;106(8-9):755-64. doi: 10.1016/j.ultramic.2005.12.010. Epub 2006 Apr 18.
Characterization of cellular structure and physical and mechanical properties of hair are essential to develop better cosmetic products and advance biological and cosmetic science. Although the morphology of the cellular structure of human hair has been traditionally investigated using scanning electron microscopy and transmission electron microscopy, these techniques provide limited capability to in situ study of the physical and mechanical properties of human hair in various environments. Atomic force microscopy (AFM) overcomes these problems and can be used for characterization in ambient conditions without requiring specific sample preparations and surface treatment. In this study, film thickness, adhesive forces and effective Young's modulus of various hair surfaces were measured at different environments (humidity and temperature) using force calibration plot technique with an AFM. Torsional resonance mode phase contrast images were also taken in order to characterize the morphology and cellular structure changes of human hair at different humidity. The correlation between the nanomechanical properties and the cellular structure of hair is discussed.
表征头发的细胞结构以及物理和机械性能对于开发更好的化妆品和推进生物及化妆品科学至关重要。尽管传统上使用扫描电子显微镜和透射电子显微镜来研究人类头发的细胞结构形态，但这些技术在原位研究人类头发在各种环境中的物理和机械性能方面能力有限。原子力显微镜（AFM）克服了这些问题，并且可以在环境条件下用于表征，而无需特定的样品制备和表面处理。在本研究中，使用带有AFM的力校准曲线技术在不同环境（湿度和温度）下测量了各种头发表面的膜厚度、粘附力和有效杨氏模量。还拍摄了扭转共振模式相衬图像，以表征不同湿度下人类头发的形态和细胞结构变化。讨论了头发的纳米力学性能与细胞结构之间的相关性。
