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[女性腹膜外直肠癌的后盆腔脏器切除术治疗]

[Posterior pelvic exenteration in the treatment of extraperitoneal rectal cancer in females].

作者信息

Zhou X G

机构信息

Ruijin Hospital, Shanghai Second Medical University.

出版信息

Zhonghua Wai Ke Za Zhi. 1991 Sep;29(9):537-9, 588.

PMID:1667517
Abstract

Postoperative recurrence is common in the, posterior vaginal wall and intrapelvic genital organs after conventional Mile's operation for extraperitoneal rectal cancer in female patients. We have performed posterior pelvic exenteration (PPE) since 1954 in an attempt to reduce such recurrences. The results of 208 patients treated by PPE were compared with those of 77 patients treated by conventional Mile's operation during 1954-1986. The 5-year survival rate of PPE was 53.15 +/- 1.87% and that of Mile's operation was 51.84 +/- 1.68%; the increase was not significant as more cases of poorer prognosis were selected for PPE. However, the local recurrence rate was lower after PPE than after conventional Mile's operation (4.33%:20.78%), (P less than 0.01). We believe that PPE is indicated in anterior rectal lesions of Dukes A, B or C stage, ulcerative or infiltrative type, or when the recto-uterine pouch is involved. PPE will not increase the operative risk if close attention is paid to hemostasis, facilitated by clamping cutting and suture ligating the lateral vaginal wall in segments.

摘要

对于女性腹膜外直肠癌患者,在进行传统的迈尔斯手术后,阴道后壁和盆腔内生殖器官的术后复发很常见。自1954年以来,我们一直进行盆腔后脏器切除术(PPE),试图减少此类复发。将208例接受PPE治疗的患者结果与1954年至1986年期间77例接受传统迈尔斯手术治疗的患者结果进行比较。PPE的5年生存率为53.15±1.87%,迈尔斯手术的5年生存率为51.84±1.68%;由于PPE选择了更多预后较差的病例,生存率的提高并不显著。然而,PPE后的局部复发率低于传统迈尔斯手术后(4.33%:20.78%),(P<0.01)。我们认为,PPE适用于Dukes A、B或C期的直肠前部病变、溃疡型或浸润型病变,或直肠子宫陷凹受累时。如果密切注意止血,通过分段钳夹切割和缝合结扎阴道侧壁来促进止血,PPE不会增加手术风险。

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