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[家兔心室3相阻滞时跨膜动作电位和单相动作电位的变化]

[Changes in transmembrane action potentials and monophasic action potentials of phase 3 intraventricular block in rabbits].

作者信息

Liu W

机构信息

First Affiliated Hospital, Hubei Medical College, Wuhan.

出版信息

Zhonghua Xin Xue Guan Bing Za Zhi. 1991 Aug;19(4):259-62, 269.

PMID:1667520
Abstract

The model of phase 3 intraventricular block was produced in 10 rabbits by giving 2.5% solution of potassium chloride intravenously under natural breathing and sinus rhythm. Transmembrane action potentials and monophasic action potentials were recorded respectively. The results showed that RP, APA, Vmax, MAPA and MVmax all decreased and both APD and MAPD shortened at the time of ventricular conduction block, when ventricular conduction was improved by vagal stimulation, RP, APA, Vmax, MAPA and MVmax all increased and both APD and MAPD lengthened. In addition, APD and MAPD measured at the same site in normal conduction, conduction block and conduction improved by vagal stimulation were in consensus.

摘要

在自然呼吸和窦性心律下,对10只家兔静脉注射2.5%氯化钾溶液,制作Ⅲ度室内传导阻滞模型。分别记录跨膜动作电位和单相动作电位。结果显示,在心室传导阻滞时,RP、APA、Vmax、MAPA和MVmax均降低,APD和MAPD均缩短;当通过迷走神经刺激改善心室传导时,RP、APA、Vmax、MAPA和MVmax均升高,APD和MAPD均延长。此外,在正常传导、传导阻滞以及迷走神经刺激改善传导时,于同一部位测得的APD和MAPD结果一致。

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