Aimoto Y, Ito K, Moriwaka F, Tashiro K, Abe K
Department of Neurology, Hokkaido University School of Medicine, Sapporo, Japan.
Jpn J Psychiatry Neurol. 1991 Dec;45(4):861-4. doi: 10.1111/j.1440-1819.1991.tb00525.x.
This is a report of a 20-year-old man with typical features of Devic disease (neuromyelitis optica) associated with demyelinating peripheral neuropathy. A sural nerve biopsy showed markedly decreased myelinated fibers of a large diameter. Teased fiber preparations showed segmental remyelination in 50% of examined fibers, as well as a few demyelination. Demyelination of bilateral optic nerves, spinal cord, and peripheral nerves at the same time suggests a possibility of common pathogenetic mechanisms in both the central and peripheral nervous systems.
这是一份关于一名20岁男性的报告，该患者具有视神经脊髓炎（Devic病）的典型特征，并伴有脱髓鞘性周围神经病。腓肠神经活检显示大直径有髓纤维明显减少。 teased纤维制备显示50%的检查纤维有节段性再髓鞘化，以及少数脱髓鞘情况。双侧视神经、脊髓和周围神经同时发生脱髓鞘提示中枢和周围神经系统可能存在共同的发病机制。
