Gilhuis H J, Otaredian I, Pomp J, Sillevis Smitt P A E
Reinier de Graaf Gasthuis, Delft.
Ned Tijdschr Geneeskd. 2006 Apr 15;150(15):821-4.
Three male patients aged 82, 56 and 60 years presented with cognitive impairment and hemiparesis, weakness of the tongue and facial muscles, and pain and weakness of the left arm, respectively. They were found to have carcinoma of the prostate with cerebral, skull and cervical spine metastases. They were treated with hormonal therapy and local radiotherapy for bone metastases. The first patient died within 2 weeks, the second after 1.5 year, and the third was still alive after 6 years. The diagnostic work-up in men with unexplained neurological symptoms should probably include a rectal exam and assessment of prostate-specific antigen.
三名男性患者，年龄分别为82岁、56岁和60岁，分别出现认知障碍和偏瘫、舌肌和面部肌肉无力以及左臂疼痛和无力症状。他们被发现患有前列腺癌并伴有脑、颅骨和颈椎转移。他们接受了激素治疗和针对骨转移的局部放疗。第一名患者在2周内死亡，第二名患者在1.5年后死亡，第三名患者在6年后仍然存活。对于有无法解释的神经症状的男性，诊断检查可能应包括直肠检查和前列腺特异性抗原评估。
