Rhoney Denise H, Liu-DeRyke Xi
Department of Pharmacy Practice, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, 259 Mack Avenue, Detroit, MI 48201, USA.
Crit Care Clin. 2006 Apr;22(2):221-43, vi. doi: 10.1016/j.ccc.2006.02.009.
Many questions regarding blood pressure management after acute stroke remain unanswered, resulting in an ongoing debate about whether to treat hypertension acutely and how aggressively blood pressure should be lowered. This review discusses normal and altered cerebrophysiology and provides evidence supporting and opposing the active management of blood pressure within the first 24 hours after stroke. Commonly used intravenous antihypertensive agents and their cerebrovascular effects are reviewed, and therapeutic recommendations are given based on the available evidence.
关于急性卒中后血压管理的许多问题仍未得到解答，这引发了一场关于是否应在急性期治疗高血压以及血压应降低到何种程度的持续争论。本综述讨论了正常和改变的脑生理学，并提供了支持和反对在卒中后24小时内积极管理血压的证据。回顾了常用的静脉降压药物及其脑血管效应，并根据现有证据给出了治疗建议。
