Macara Ian G, Spang Anne
Center for Cell Signaling, Department of Microbiology, University of Virginia, Charlottesville, VA 22908, USA.
Cell. 2006 May 5;125(3):419-21. doi: 10.1016/j.cell.2006.04.011.
How are tight junctions maintained? In this issue of Cell, Wells et al. (2006) provide intriguing evidence for a new pathway that links polarity proteins and vesicle transport to the maintenance of tight junctions, through the control of Cdc42 by Rich1, a GTPase-activating protein.
紧密连接是如何维持的？在本期《细胞》杂志中，韦尔斯等人（2006年）提供了有趣的证据，证明了一条新的途径，即通过一种GTP酶激活蛋白Rich1对Cdc42的控制，将极性蛋白和囊泡运输与紧密连接的维持联系起来。
