Dahm Philipp
Division of Urologic Surgery, Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA.
Curr Opin Urol. 2006 May;16(3):162-7. doi: 10.1097/01.mou.0000193395.00340.3e.
A majority of medical decisions relating to the diagnosis, prognosis, and therapy of prostate cancer are based on low levels of evidence. This article reviews the recommendations of currently available evidence-based practice guidelines that relate to the management of patients with newly diagnosed prostate cancer. The article further introduces a selection of recent studies that are relevant to the evidence-based patient care.
Updated clinical practice guidelines on the management of prostate-cancer patients provide an evidence-based summary of the literature and have recently been made available through the National Cancer Center Network and the European Urological Association. In addition, several recent high-quality studies have made major contributions to our knowledge of the natural history and therapy of prostate cancer.
The efforts of professional associations to generate evidence-based guidelines are reflective of an increased awareness that the care of prostate cancer should--to the greatest possible extent--be evidence-based. Practicing urologists should seek to become involved in the evidence-based medicine process by supporting the accrual to high-quality clinical trials, demanding the highest standards to the timely and unbiased dissemination of research findings and ultimately, strive to apply the best available evidence to the care of individual patients.
大多数与前列腺癌诊断、预后及治疗相关的医学决策都基于低水平证据。本文回顾了当前可用的循证实践指南中与新诊断前列腺癌患者管理相关的建议。本文还介绍了一些与循证患者护理相关的近期研究。
关于前列腺癌患者管理的最新临床实践指南对文献进行了循证总结，最近已通过美国国立综合癌症网络和欧洲泌尿外科学会发布。此外，近期的几项高质量研究对我们了解前列腺癌的自然史和治疗方法做出了重大贡献。
专业协会制定循证指南的努力反映出人们越来越意识到，前列腺癌的治疗应尽可能基于证据。执业泌尿科医生应通过支持参与高质量临床试验、要求以最高标准及时、公正地传播研究结果，并最终努力将最佳可用证据应用于个体患者的护理，来参与循证医学过程。
