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Early foetal programming of hepatic gluconeogenesis: Glucocorticoids strike back.

作者信息

McCurdy C E, Friedman J E

机构信息

Department of Pediatrics, University of Colorado School of Medicine, Mail Stop 8106, Aurora, CO, 80045, USA.

出版信息

Diabetologia. 2006 Jun;49(6):1138-41. doi: 10.1007/s00125-006-0256-x.

DOI:10.1007/s00125-006-0256-x
PMID:16680490
Abstract
摘要

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Early foetal programming of hepatic gluconeogenesis: Glucocorticoids strike back.
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Comment on: Nyirenda MJ, Dean S, Lyons V, Chapman KE, Seckl JR (2006) Prenatal programming of hepatocyte nuclear factor 4a in the rat: a key mechanism in the 'foetal origins of hyperglycaemia'? Diabetologia 49: 1412-1420, and on: McCurdy CE, Friedman JE (2006) Early foetal programming of hepatic gluconeogenesis: glucocorticoids strike back. Diabetologia 49:1138-1141.评论：Nyirenda MJ、Dean S、Lyons V、Chapman KE、Seckl JR（2006年）大鼠肝细胞核因子4α的产前编程：“高血糖胎儿起源”中的关键机制？《糖尿病学》49卷：1412 - 1420页；以及评论：McCurdy CE、Friedman JE（2006年）肝脏糖异生的早期胎儿编程：糖皮质激素反击。《糖尿病学》49卷：1138 - 1141页。
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Comment on: Nyirenda MJ, Dean S, Lyons V, Chapman KE, Seckl JR (2006) Prenatal programming of hepatocyte nuclear factor 4a in the rat: a key mechanism in the 'foetal origins of hyperglycaemia'? Diabetologia 49: 1412-1420, and on: McCurdy CE, Friedman JE (2006) Early foetal programming of hepatic gluconeogenesis: glucocorticoids strike back. Diabetologia 49:1138-1141.

本文引用的文献

1
Prenatal programming of hepatocyte nuclear factor 4alpha in the rat: A key mechanism in the 'foetal origins of hyperglycaemia'?大鼠肝细胞核因子4α的产前编程：“高血糖胎儿起源”的关键机制？
Diabetologia. 2006 Jun;49(6):1412-20. doi: 10.1007/s00125-006-0188-5. Epub 2006 Mar 29.
2
Fetal growth and the adrenocortical response to psychological stress.胎儿生长与肾上腺皮质对心理应激的反应。
J Clin Endocrinol Metab. 2006 May;91(5):1868-71. doi: 10.1210/jc.2005-2077. Epub 2006 Feb 7.
3
Glucocorticoids regulate transcription of the gene for phosphoenolpyruvate carboxykinase in the liver via an extended glucocorticoid regulatory unit.
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Diabetologia. 2006 Nov;49(11):2809-10. doi: 10.1007/s00125-006-0423-0. Epub 2006 Sep 19.
糖皮质激素通过一个扩展的糖皮质激素调节单元来调控肝脏中磷酸烯醇式丙酮酸羧激酶基因的转录。
J Biol Chem. 2005 Oct 7;280(40):33873-84. doi: 10.1074/jbc.M504119200. Epub 2005 Aug 12.
4
The glucose-6-phosphatase catalytic subunit gene promoter contains both positive and negative glucocorticoid response elements.葡萄糖-6-磷酸酶催化亚基基因启动子包含正性和负性糖皮质激素反应元件。
Mol Endocrinol. 2005 Dec;19(12):3001-22. doi: 10.1210/me.2004-0497. Epub 2005 Jul 21.
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A maternal cafeteria diet during gestation and lactation promotes adiposity and impairs skeletal muscle development and metabolism in rat offspring at weaning.孕期和哺乳期的母体自助餐式饮食会促进大鼠后代断奶时的肥胖，并损害其骨骼肌发育和新陈代谢。
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