Grigor'ev V M, Snetkov V A
Fiziol Zh SSSR Im I M Sechenova. 1991 Jul;77(7):22-8.
The treatment of m. cutaneus pectoris-n. pectoralis preparations with 0.5 microM of alkylating derivate of hexadecamethonium, hexadecamethylene-bis-methylchloroethylamine, led to irreversible decrease of the amplitude of EPPs. The decrease was shown to be of a postsynaptic nature. After pretreatment of the neuromuscular preparations with alkylating derivate the effects of cholinesterase inhibitors were strongly diminished.
用0.5微摩尔十六甲基溴化铵的烷基化衍生物十六亚甲基 - 双 - 甲基氯乙胺处理胸皮肌 - 胸神经制剂，导致终板电位（EPPs）幅度不可逆降低。这种降低显示为突触后性质。在用烷基化衍生物对神经肌肉制剂进行预处理后，胆碱酯酶抑制剂的作用大大减弱。
