[近端小肠切除对胃泌素诱导的胃酸分泌抑制作用的影响]
[The effect of resection of the proximal small intestine on the inhibition of gastric secretion induced by gastrotsepin].
作者信息
Trefilov A B
出版信息
Fiziol Zh SSSR Im I M Sechenova. 1991 Jul;77(7):70-5.
PMID:1668162
Abstract
The removal of the proximal 1/3 part of the intestine led to reduction of "spontaneous" inhibition of gastric secretion caused by gastrocepin provoking selective blockade of gastric M-cholinoreceptors in rats with gastric fistulae. The enteral mechanisms regulating gastric secretion, seem to participate in this inhibition and gastric M-cholinoreceptors seem to change their function under the influence of enterogastric activity.
摘要
切除大鼠近端1/3肠段可导致胃泌素引起的“自发性”胃分泌抑制作用减弱，胃泌素可选择性阻断胃瘘大鼠的胃M胆碱能受体。调节胃分泌的肠内机制似乎参与了这种抑制作用，并且胃M胆碱能受体在肠胃活动的影响下似乎会改变其功能。
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