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[小肠近端切除与切断术后胃腺壁细胞分泌肾上腺素能抑制的变化]

[Changes in adrenergic inhibition of the secretion of parietal cells of gastric glands after resection and section of the proximal portion of the small intestine].

作者信息

Trefilov A B

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1985 Dec;71(12):1597-601.

PMID:4092778
Abstract

Semi-chronic experiments on rats with the gastric fistula showed that the removal of the intestinal proximal 1/3 resulted in practically complete disturbance of adrenergic inhibition of the "spontaneous" gastric secretion (inhibition was caused by submaximal adrenaline dose). The intestinal dissection on the level of cranial and caudal resection borders is also accompanied by the inhibition reduction though less obvious. The nervous and humoral mechanisms of the proximal portion of the intestine seem to participate in the adrenal inhibition of the gastric secretion.

摘要

对患有胃瘘的大鼠进行的半慢性实验表明,切除肠道近端三分之一实际上会导致肾上腺素能对“自发性”胃分泌的抑制作用完全紊乱(这种抑制是由次最大剂量的肾上腺素引起的)。在颅侧和尾侧切除边界水平进行肠切断术也会伴随着抑制作用的降低,尽管不太明显。肠道近端的神经和体液机制似乎参与了肾上腺素对胃分泌的抑制作用。

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