调节盘基网柄菌发育的环磷酸腺苷信号转导途径
cAMP signal transduction pathways regulating development of Dictyostelium discoideum.
作者信息
Kimmel A R, Firtel R A
机构信息
Laboratory of Cellular and Developmental Biology, NIDDK/NIH, Bethesda, Maryland 20892.
出版信息
Curr Opin Genet Dev. 1991 Oct;1(3):383-90. doi: 10.1016/s0959-437x(05)80304-1.
PMID:1668648
Abstract
Dictyostelium discoideum development is regulated through receptor/G protein signal transduction using cAMP as a primary extracellular signal. Signaling pathways will be discussed as well as the regulation and function of individual cAMP receptors and G alpha subunits. Finally potential downstream targets including protein kinases and nuclear events will be explored.
摘要
盘基网柄菌的发育通过以环磷酸腺苷（cAMP）作为主要细胞外信号的受体/G蛋白信号转导进行调控。我们将讨论信号通路以及各个cAMP受体和Gα亚基的调控与功能。最后，我们将探讨包括蛋白激酶和核事件在内的潜在下游靶点。
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