Hennies Felix, Jappe Uta, Kapaun Annette, Enk Alexander
Department of Dermatology, University of Heidelberg, Germany.
J Dtsch Dermatol Ges. 2006 May;4(5):414-6. doi: 10.1111/j.1610-0387.2006.05942.x.
Gnathostomiasis is a nematode infestation endemic in Southeast Asia, which can involve multiple organs including the liver, eyes, gastrointestinal tract and CNS. The most common manifestation is recurrent migratory subcutaneous swellings which can appear anywhere on the body and are accompanied by pruritus and systemic symptoms such as low-grade fever, loss of appetite and nausea. The diagnosis is based on the clinical picture, history of travel, peripheral blood eosinophilia and the determination of agent-specific antibody levels. The standard treatment is albendazole. We present a 37-year-old Laotian woman, who had lived in Germany for 17 years, but developed recurrent swelling of the cheek following a visit to Laos. Because of the typical clinical findings, the history of a visit to Laos, and the presence of specific anti-Gnathostoma antibodies on Western blot, the diagnosis of cutaneous gnathostomiasis was made.
颚口线虫病是一种在东南亚流行的线虫感染病，可累及包括肝脏、眼睛、胃肠道和中枢神经系统在内的多个器官。最常见的表现是反复出现的游走性皮下肿胀，可出现在身体的任何部位，并伴有瘙痒以及低热、食欲不振和恶心等全身症状。诊断基于临床表现、旅行史、外周血嗜酸性粒细胞增多以及特定病原体抗体水平的测定。标准治疗方法是使用阿苯达唑。我们报告一名37岁的老挝女性，她在德国生活了17年，但在访问老挝后出现了脸颊反复肿胀的情况。由于典型的临床症状、访问老挝的病史以及免疫印迹法检测到存在特定的抗颚口线虫抗体，故诊断为皮肤颚口线虫病。
