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[巨细胞病毒引起的传染性单核细胞增多症样综合征]

[Infectious mononucleosis-like syndrome caused by Cytomegaloviruses].

作者信息

Janeczko J

机构信息

Klinika Chorób Zakaźnych dla Doroslych Instytutu Chorób Zakaźnych, Pasozytniczych Akademii Medycznej, Warszawie.

出版信息

Przegl Epidemiol. 1991;45(4):257-61.

PMID:1668699
Abstract

The detailed clinical, hematological, and biochemical analysis performed in 332 patients in whom infectious mononucleosis had been diagnosed or suspected revealed the mononucleosis-like syndrome due to Cytomegalovirus infection in 4.5%. This diagnosis was confirmed by the presence of specific antibodies in the ELISA methods (most frequent titres 1:1600 and 1:3200) and or by the CFT (mostly 1:64 and 1:128). The diagnosis of infectious mononucleosis was confirmed in the Paul-Bunnell-Davidsohn test in the titre was greater than or equal to 1:56. Attention is drawn to the differences regarding the clinical signs as well as the clinical and biochemical parameters between the mononucleosis-like syndrome and the infectious mononucleosis. The clinical diagnosis of this syndrome is difficult however possible, if kept, in mind and if all the parameters are properly analysed. This diagnosis has to be always confirmed by serologic test.

摘要

对332例已确诊或疑似传染性单核细胞增多症的患者进行的详细临床、血液学和生化分析显示,4.5%的患者患有由巨细胞病毒感染引起的类单核细胞增多症综合征。通过ELISA方法检测到特异性抗体(最常见的滴度为1:1600和1:3200)和/或通过补体结合试验(大多为1:64和1:128)证实了这一诊断。在保罗-邦内尔-戴维森试验中,滴度大于或等于1:56可确诊传染性单核细胞增多症。请注意类单核细胞增多症综合征与传染性单核细胞增多症在临床体征以及临床和生化参数方面的差异。该综合征的临床诊断虽有困难,但如果牢记在心并对所有参数进行恰当分析则是可能的。这一诊断必须始终通过血清学检测来证实。

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