Andreassen R, Jakobsen S, Mevaag B
Institute of Forensic Medicine, University of Oslo, Rikshospitalet, 0027 Oslo, Norway.
Forensic Sci Int. 2007 Jul 20;170(1):59-61. doi: 10.1016/j.forsciint.2006.03.026. Epub 2006 May 9.
Allele frequencies of the STR loci included in the AmpFlSTR SGM Plus kit were determined in 1000 unrelated individuals from all regions of Norway. For the 10 autosomal STR loci the observed heterozygosity frequencies ranged from 0.766 (D16S539) to 0.885 (D2S1338). No significant deviation from Hardy-Weinberg equilibrium was observed. The exact test disequilibrium analysis revealed one departure from independence out of 45 pairwise comparisons. Calculations of theta coefficients for all 10 loci in two additional subpopulations of different geographical origin revealed an overall value of theta=0.002.
在来自挪威所有地区的1000名无关个体中,测定了AmpFlSTR SGM Plus试剂盒中所含STR基因座的等位基因频率。对于10个常染色体STR基因座,观察到的杂合子频率范围为0.766(D16S539)至0.885(D2S1338)。未观察到与哈迪-温伯格平衡的显著偏差。精确检验不平衡分析显示,在45次成对比较中有一次偏离独立性。对另外两个不同地理来源的亚群中所有10个基因座的θ系数计算显示,θ的总体值为0.002。