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物质使用障碍患者中反社会人格障碍与精神疾病的关联。

Association of antisocial personality disorder with psychiatric morbidity among patients with substance use disorder.

作者信息

Westermeyer Joseph, Thuras Paul, Carlson Gregory

机构信息

Minneapolis VAMC, Minneapolis, MN, USA.

出版信息

Subst Abus. 2005 Jun;26(2):15-24. doi: 10.1300/j465v26n02_03.

Abstract

OBJECTIVES

The aims were to determine among patients with Substance Use Disorder (SUD) whether patients with Antisocial Personality Disorder (ASPD) manifest less, the same, or more of the following: (1) psychiatric symptoms, (2) family history of psychiatric disorder, (3) psychiatric disorders and morbidity, and (4) psychiatric treatment, as compared to patients without ASPD.

DESIGN & DEFINITION: Scheduled interview using DSM-III-R criteria for ASPD, with blinded interviewers making the ASPD classification vs. other assessments.

SETTINGS

Alcohol-drug treatment programs located in two university medical centers.

SUBJECTS

Six hundred and six voluntary patients aged 18 and older meeting diagnostic criteria for SUD.

RESULTS

SUD patients with ASPD reported more family history of non-SUD psychiatric diagnoses and endorsed more hostility symptoms. Demographic characteristics, psychiatric disorder, and past psychiatric treatment did not differ in association with ASPD.

摘要

目的

旨在确定在物质使用障碍(SUD)患者中,与无反社会人格障碍(ASPD)的患者相比,患有反社会人格障碍(ASPD)的患者在以下方面表现得更少、相同还是更多:(1)精神症状,(2)精神障碍家族史,(3)精神障碍及发病率,以及(4)精神治疗情况。

设计与定义

使用DSM-III-R标准对ASPD进行定期访谈,由不知情的访谈者进行ASPD分类及其他评估。

地点

位于两个大学医学中心的酒精-药物治疗项目。

研究对象

606名年龄在18岁及以上、符合SUD诊断标准的自愿患者。

结果

患有ASPD的SUD患者报告有更多非SUD精神诊断的家族史,并认可更多敌对症状。人口统计学特征、精神障碍及既往精神治疗情况在与ASPD的关联方面并无差异。

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