锶取代羟基磷灰石的力学性能和溶解性
The mechanical properties and solubility of strontium-substituted hydroxyapatite.
作者信息
Okayama S, Akao M, Nakamura S, Shin Y, Higashikata M, Aoki H
机构信息
Division of Inorganic Materials, Tokyo Medical and Dental University, Japan.
出版信息
Biomed Mater Eng. 1991;1(1):11-7.
The mechanical properties and solubility of sintered Sr-substituted hydroxyapatites were examined in order to investigate the influences of Sr incorporation into hydroxyapatite in bones and teeth on them. Hydroxyapatite (HAp), Sr-substituted hydroxyapatite (Ca.SrAp), and strontium-hydroxyapatite (SrAp) were synthesized and sintered. The bending strength and Young's modulus were measured. Also, solubility in isotonic NaCl solution was examined. The Young's modulus of Sr-substituted hydroxyapatite (Sr wt% = 1.0) and hydroxyapatite surface treated with Sr ion were greater than that of hydroxyapatite. The bending strengths of Sr-substituted hydroxyapatites (Sr/Ca = 4/6 and less) were reduced slightly compared to that of hydroxyapatite. The bending strength of hydroxyapatite surface treated with Sr ion was increased compared to that of hydroxyapatite. The solubility in isotonic NaCl solution at 37 degrees C was increased with an increase in Sr content. The effects of Sr on the mechanical properties and solubility of bones and/or teeth are discussed.
为了研究锶掺入骨骼和牙齿中的羟基磷灰石对其力学性能和溶解性的影响，对烧结的锶取代羟基磷灰石的力学性能和溶解性进行了研究。合成并烧结了羟基磷灰石（HAp）、锶取代羟基磷灰石（Ca.SrAp）和锶羟基磷灰石（SrAp）。测量了弯曲强度和杨氏模量。此外，还检测了在等渗氯化钠溶液中的溶解性。锶取代羟基磷灰石（锶重量百分比 = 1.0）和经锶离子表面处理的羟基磷灰石的杨氏模量大于羟基磷灰石。与羟基磷灰石相比，锶取代羟基磷灰石（锶/钙 = 4/6及以下）的弯曲强度略有降低。经锶离子表面处理的羟基磷灰石的弯曲强度比羟基磷灰石有所增加。在37℃下，等渗氯化钠溶液中的溶解度随锶含量的增加而增加。讨论了锶对骨骼和/或牙齿力学性能和溶解性的影响。
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