使用羟基磷灰石柱吸附和制备人类病毒。
Adsorption and preparation of human viruses using hydroxyapatite column.
作者信息
Tsuru S, Shinomiya N, Katsura Y, Uwabe Y, Noritake M, Rokutanda M
机构信息
Department of Microbiology, National Defense Medical College, Saitama, Japan.
出版信息
Biomed Mater Eng. 1991;1(3):143-7.
PMID:1668797
Abstract
The adsorption and chromatographic properties of hydroxyapatite sorbents for application to different viruses have been investigated. The strong adsorption of viruses was observed on macroporous hydroxyapatite with hydrophilic properties of the sorbent surface. The viruses were purified on this sorbent without loss of biological activity. The column can be used for virus vaccine production.
摘要
研究了用于不同病毒的羟基磷灰石吸附剂的吸附和色谱特性。在具有吸附剂表面亲水性的大孔羟基磷灰石上观察到病毒的强吸附。在这种吸附剂上对病毒进行了纯化，且生物活性没有损失。该柱可用于病毒疫苗生产。
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