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预测早期气管切开术的需求:对992例插管创伤患者的多因素分析

Predicting the need for early tracheostomy: a multifactorial analysis of 992 intubated trauma patients.

作者信息

Goettler Claudia E, Fugo Jonathan R, Bard Michael R, Newell Mark A, Sagraves Scott G, Toschlog Eric A, Schenarts Paul J, Rotondo Michael F

机构信息

Department of Surgery, East Carolina University, Greenville, North Carolina, USA.

出版信息

J Trauma. 2006 May;60(5):991-6. doi: 10.1097/01.ta.0000217270.16860.32.

Abstract

BACKGROUND

Tracheostomy has few, severe risks, while prolonged endotracheal intubation causes morbidity. The need for tracheostomy was assessed, based on early clinical parameters.

METHODS

Adult trauma patients (January 1994-August 2004), intubated for resuscitation, ventilated >24 hours, were retrospectively evaluated for demographics, physiology, brain, and pulmonary injury. Tracheostomy patients were compared with those without. Chi-square, Mann-Whitney, and multivariate logistic regression were used with statistical significance at p < 0.05.*

RESULTS

Of 992 patients, 430 (43%) underwent tracheostomy at 9.22 +/- 5.7 days. Risk factors were age (45.6* +/- 18.8 vs. 36.7 +/- 15.9, OR: 2.1 (18 years increments), ISS (30.3* +/- 12.5 vs. 22.0 +/- 10.3, OR: 2.1 (12u increments), damage control (DC) [68%(n = 51) vs. 32%(n = 51), OR: 3.8], craniotomy [70%(n = 21) versus 30%(n = 9), OR: 2.6], and intracranial pressure monitor (ICP) [65.4%(n = 87) vs. 34.6%(n = 46), OR: 2.1]. A 100% tracheostomy rate (n = 30, 3.0%) occurred with ISS (injury severity score) = 75, ISS >or=50, and age >or=55, admit/24 hour GCS (Glasgow Coma Scale) = 3 and age >or=70, AIS abdomen, chest or extremities >or=5 and age >or=60, bilateral pulmonary contusions (BPC) and >or=8 rib fractures, craniotomy and age >or=50, craniotomy with intracranial pressure (ICP) and age >or=40, or craniotomy and GCS <or=4 at 24 hour.A tracheostomy rate of >or=90% (n = 105, 10.6%) was found with ISS >or=54, ISS >or=40, and age >or=40, admit/24 hour GCS = 3 and age >or=55, paralysis and age >or=40, BPC and age >or=55.A tracheostomy rate >or=80% (n = 248, 25.0%) occurred with ISS >or=38, age >or=80, admit/24 hour GCS = 3 and age >or=45, DC and age >or=50, BPC and age >or=50, aspiration and age >or=55, craniotomy with ICP, craniotomy with GCS <or=9 at 24 hour.

CONCLUSION

Discrete risk factors predict the need for tracheostomy for trauma patients. We recommend that patients with >or=90% risk undergo early tracheostomy and that it is considered in the >or=80% risk group to potentially decreased morbidity, increased patient comfort, and optimize resource utilization.

摘要

背景

气管切开术风险少且严重程度低,而长时间气管插管会引发并发症。基于早期临床参数对气管切开术的必要性进行了评估。

方法

对1994年1月至2004年8月因复苏而行气管插管、机械通气超过24小时的成年创伤患者的人口统计学、生理学、脑和肺损伤情况进行回顾性评估。将行气管切开术的患者与未行气管切开术的患者进行比较。采用卡方检验、曼-惠特尼检验和多因素逻辑回归分析,p<0.05为具有统计学意义。

结果

992例患者中,430例(43%)在9.22±5.7天接受了气管切开术。危险因素包括年龄(45.6±18.8岁对36.7±15.9岁,比值比:2.1(每增加18岁))、损伤严重度评分(ISS)(30.3±12.5对22.0±10.3,比值比:2.1(每增加12分))、损害控制(DC)[68%(n = 51)对32%(n = 51),比值比:3.8]、开颅手术[70%(n = 21)对30%(n = 9),比值比:2.6]以及颅内压监测(ICP)[65.4%(n = 87)对34.6%(n = 46),比值比:2.1]。当ISS=75、ISS≥50且年龄≥55岁、入院/24小时格拉斯哥昏迷量表(GCS)=3且年龄≥70岁、简明损伤定级(AIS)腹部、胸部或四肢≥5且年龄≥60岁、双侧肺挫伤(BPC)且肋骨骨折≥8根、开颅手术且年龄≥50岁、开颅手术伴颅内压(ICP)且年龄≥40岁或开颅手术且24小时GCS≤4时,气管切开率为100%(n = 30,3.0%)。当ISS≥54、ISS≥40且年龄≥40岁、入院/24小时GCS = 3且年龄≥55岁、瘫痪且年龄≥40岁、BPC且年龄≥55岁时,气管切开率≥90%(n = 105,10.6%)。当ISS≥38、年龄≥80岁、入院/24小时GCS = 3且年龄≥45岁、DC且年龄≥50岁、BPC且年龄≥50岁、误吸且年龄≥55岁、开颅手术伴ICP、开颅手术且24小时GCS≤9时,气管切开率≥80%(n = 248,25.0%)。

结论

特定危险因素可预测创伤患者对气管切开术的需求。我们建议,风险≥90%的患者应尽早行气管切开术,对于风险≥80%的患者也应考虑行气管切开术,以潜在降低并发症发生率、提高患者舒适度并优化资源利用。

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