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再次入住外科重症监护病房会增加经病情严重程度调整后的患者死亡率。

Readmission to surgical intensive care increases severity-adjusted patient mortality.

作者信息

Alban Rodrigo F, Nisim Abraham A, Ho Jocelyn, Nishi Gregg K, Shabot M Michael

机构信息

Burns and Allen Research Institute, Department of Surgery, Cedars-Sinai Medical Center, CA 90048, USA.

出版信息

J Trauma. 2006 May;60(5):1027-31. doi: 10.1097/01.ta.0000218217.42861.b7.

Abstract

BACKGROUND

This study aims to determine whether severity-adjusted outcomes including mortality are adversely impacted by readmission to a surgical intensive care unit (SICU) during the same hospital stay.

METHODS

The study included all patients admitted to the 20-bed tertiary care SICU in an urban teaching Level I trauma center and multiorgan transplant center from January 1, 1996 to December 31, 2001. This was a prospective observational study with secondary data analysis. Acute Physiology and Chronic Health Evaluation (APACHE II) and Simplified Acute Physiology (SAPS) severity scores were calculated by a clinical information system. Outcomes were extracted from a computerized data warehouse.

RESULTS

In-hospital mortality and SICU length of stay (LOS) were measured for patients admitted and readmitted to the SICU. Of 10,840 patients admitted to the SICU, 296 (2.73%) required readmission to the SICU during the same hospital stay. The length of the original SICU stay was 4.9 +/- 6.7 days for readmitted patients compared with 3.2 +/- 6.0 days for nonreadmitted patients (p < 0.001). Readmitted patients had a higher mean APACHE II score on the day of original SICU discharge compared with nonreadmitted patients, 15.7 +/- 6.7 versus 13.8 +/- 7.1 (p < 0.001). The average APACHE II score increased from 15.7 +/- 6.7 to 18.1 +/- 8.6 between the day of SICU discharge and readmission (p < 0.001) and SAPS increased from 12.2 +/- 4.8 to 13.5 +/- 5.4 (p < 0.001). The distributions of severity-adjusted hospital mortality for both APACHE II and SAPS revealed that readmission to the SICU significantly increased mortality independent of the admission severity score.

CONCLUSIONS

Readmission to the SICU significantly increases the risk of death beyond that predicted by the APACHE II or SAPS scores alone. Higher APACHE II and SAPS scores upon discharge from the SICU and longer SICU LOS are associated with an increased incidence of readmission to the SICU on the same hospital stay. These results may be used to optimize the timing of SICU discharge and reduce the chance of readmission to intensive care.

摘要

背景

本研究旨在确定在同一住院期间再次入住外科重症监护病房(SICU)是否会对包括死亡率在内的严重程度调整后的结果产生不利影响。

方法

该研究纳入了1996年1月1日至2001年12月31日期间入住一家城市教学一级创伤中心和多器官移植中心拥有20张床位的三级护理SICU的所有患者。这是一项进行二次数据分析的前瞻性观察性研究。急性生理与慢性健康评估(APACHE II)和简化急性生理学(SAPS)严重程度评分由临床信息系统计算得出。结果从计算机化数据仓库中提取。

结果

对入住和再次入住SICU的患者测量了住院死亡率和SICU住院时长(LOS)。在入住SICU的10840例患者中,296例(2.73%)在同一住院期间需要再次入住SICU。再次入住患者最初的SICU住院时长为4.9±6.7天,而非再次入住患者为3.2±6.0天(p<0.001)。与非再次入住患者相比,再次入住患者在最初SICU出院当天的平均APACHE II评分更高,分别为15.7±6.7和13.8±7.1(p<0.001)。在SICU出院当天至再次入住期间,平均APACHE II评分从15.7±6.7增加至18.1±8.6(p<0.001),SAPS评分从12.2±4.8增加至13.5±5.4(p<0.001)。APACHE II和SAPS的严重程度调整后的医院死亡率分布显示,再次入住SICU显著增加了死亡率,且与入院严重程度评分无关。

结论

再次入住SICU显著增加了死亡风险,超出了仅由APACHE II或SAPS评分预测的范围。SICU出院时较高的APACHE II和SAPS评分以及较长的SICU住院时长与同一住院期间再次入住SICU的发生率增加相关。这些结果可用于优化SICU出院时间并减少再次入住重症监护病房的机会。

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