Zhavrid E A, Sachivko N V, Fradkin S Z, Rud'ko A S
Vopr Onkol. 1991;37(9-10):962-7.
Treatment results were compared in 2 groups of patients with advanced small-cell lung cancer. Group 1 (52 cases) received chemoradiation treatment alone whereas in group 2 (41 patients) it was combined with general hyperthermia (temperature 40-41.8 degrees C during 3-4 hours). Response was observed in 63.5% of patients of group 1 and 79.5% of those in group 2. Complete response rates did not differ significantly (23.1 and 28.2%, respectively). 40.6 +/- 8.2% of patients receiving chemoradiation treatment plus general hyperthermia survived over 1 year, 20.5 +/- 7.1%--over 1.5 years and 15.9 +/- 6.7%--over 2 years. In the control group, the respective rates were 22.2 +/- 5.8%, 5.1 +/- 3.4% and 5.1 +/- 3.4%.
对两组晚期小细胞肺癌患者的治疗结果进行了比较。第一组（52例）仅接受放化疗，而第二组（41例）则联合全身热疗（温度在40 - 41.8摄氏度，持续3 - 4小时）。第一组63.5%的患者出现反应，第二组为79.5%。完全缓解率无显著差异（分别为23.1%和28.2%）。接受放化疗加全身热疗的患者中，40.6±8.2%存活超过1年，20.5±7.1%存活超过1.5年，15.9±6.7%存活超过2年。在对照组中，相应的比例分别为22.2±5.8%、5.1±3.4%和5.1±3.4%。
