Jensen-Urstad Mats, Tabrizi Fariborz, Kennebäck Göran, Wredlert Christer, Klang Caroline, Insulander Per
Karolinska Institute, Department of Cardiology, Karolinska University Hospital, Huddinge, Stockholm, Sweden.
Pacing Clin Electrophysiol. 2006 May;29(5):487-9. doi: 10.1111/j.1540-8159.2006.00380.x.
Cryoablation is a new alternative to radiofrequency (RF) ablation for treatment of atrioventricular nodal reentry tachycardias (AVNRT). Mapping with reversible effect on the arrhythmia substrate or the AV node can be done before irreversible ablation is performed. This study evaluates an approach with systematic cryomapping, ablating only in areas with prompt effect on the arrhythmia substrate and evaluates whether the success rates and procedure times are similar to RF ablation.
Seventy-five consecutive patients with typical slow-fast AVNRT were studied. Cryomapping at -30 degrees C was performed before ablation with a goal temperature of -70 degrees C for 240 seconds. The ablation procedure was successful in 74 of the 75 patients, giving an acute success rate of 99%. During a mean follow-up of 338 days, 70 of the 74 primarily successfully ablated patients were free from the treated arrhythmia, giving a recurrence rate of 5% and a total success rate of 93%. Total procedure time including a 30-minute test after successful ablation was 126+/-55 minutes. Fluoroscopy time was 18.5+/-14.9 minutes.
Cryoablation of AVNRT appears to be as effective as RF ablation both acute and in long term with minimal risks for unwanted injuries on the conduction system. The procedure can be done with reasonable procedure and fluoroscopy times.
冷冻消融是治疗房室结折返性心动过速(AVNRT)的一种替代射频(RF)消融的新方法。在进行不可逆消融之前,可以对心律失常基质或房室结进行具有可逆作用的标测。本研究评估了一种采用系统冷冻标测的方法,仅在对心律失常基质有迅速作用的区域进行消融,并评估成功率和手术时间是否与射频消融相似。
对75例连续性典型慢快型AVNRT患者进行了研究。在消融前于-30℃进行冷冻标测,目标温度为-70℃,持续时间为240秒。75例患者中有74例消融手术成功,急性成功率为99%。在平均338天的随访期间,74例最初消融成功的患者中有70例未发生所治疗的心律失常,复发率为5%,总成功率为93%。包括消融成功后30分钟测试在内的总手术时间为126±55分钟。透视时间为18.5±14.9分钟。
AVNRT的冷冻消融在急性和长期效果上似乎与射频消融一样有效,对传导系统造成意外损伤的风险最小。该手术可以在合理的手术时间和透视时间内完成。