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[支气管肺泡灌洗术(BAL)在评估艾滋病患者肺部损害中的作用]

[The role of bronchoalveolar lavage (BAL) in assessing pulmonary compromise in AIDS].

作者信息

Perna F, Sanduzzi A, Ponticiello A

机构信息

Cattedra delle Malattie dell'Apparato Respiratorio, II Facoltà di Medicina e Chirurgia, Università degli Studi di Napoli.

出版信息

Arch Monaldi Mal Torace. 1990 Jul-Aug;45(4):269-77.

PMID:1669281
Abstract

The severe immunologic alterations caused by HIV infection is at the base of respiratory tract infections, neoplasms and inflammatory complications which represent the most frequent cause of death in AIDS patients. The etiological diagnosis is difficult and often needs invasive procedures. Among those, BAL is surely the most useful method because of its lesser invasiveness and better tolerability and more for its sensibility and easier repeatability. Besides the etiological evaluation of lung infections, BAL allows to obtain and analyze immunologic and inflammatory cells from alveolar spaces consenting the acquisition of data regarding immunopathogenetic mechanisms related to pulmonary complications during AIDS. We report data about cytoimmunologic study of BAL fluid in 10 patients of ours.

摘要

由HIV感染引起的严重免疫改变是呼吸道感染、肿瘤和炎症并发症的基础,而这些是艾滋病患者最常见的死亡原因。病因诊断困难,且常常需要侵入性操作。其中,支气管肺泡灌洗术(BAL)肯定是最有用的方法,因为它侵入性较小、耐受性较好,更因其敏感性高且易于重复。除了对肺部感染进行病因评估外,BAL还能从肺泡腔获取并分析免疫和炎症细胞,从而获取有关艾滋病期间肺部并发症免疫发病机制的数据。我们报告了我们10例患者支气管肺泡灌洗术(BAL)液的细胞免疫学研究数据。

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