Agostini C, Zambello R, Gasparotto G
Sarcoidosis. 1986 Mar;3(1):69-74.
The lung is involved in more than 50 per cent of patients with the acquired immune deficiency syndrome (AIDS), and pulmonary abnormalities can be easily investigated using the bronchoalveolar lavage (BAL). Besides providing information on the type of infecting microorganism, BAL has been used to characterize immunocompetent cells from the lower respiratory tract in these patients. This allows new insights into the immunopathogenetic mechanism involved in the persistence of opportunistic pulmonary infections and in the uncontrolled viral replication. This paper emphasizes the value of BAL evaluation as a simple and useful method for investigating the involvement of the distal respiratory tract in AIDS patients. A particular attention is payed on the immunological pulmonary abnormalities of this epidemic immunodeficiency syndrome.
超过50%的获得性免疫缺陷综合征（艾滋病）患者肺部会受累，使用支气管肺泡灌洗（BAL）能够轻松检查出肺部异常情况。除了提供有关感染微生物类型的信息外，BAL还被用于鉴定这些患者下呼吸道的免疫活性细胞。这有助于深入了解机会性肺部感染持续存在及病毒复制失控所涉及的免疫发病机制。本文强调了BAL评估作为一种简单且有用的方法在研究艾滋病患者远端呼吸道受累情况方面的价值。尤其关注了这种流行性免疫缺陷综合征的肺部免疫异常情况。
