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诗里拉吉医院不一致双胞胎的患病率及相关因素

Prevalence and associated factors of discordant twins in Siriraj Hospital.

作者信息

Pongpanich W, Borriboonhirunsarn D

机构信息

Department of Obstetrics and Gynecology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.

出版信息

J Med Assoc Thai. 2006 Mar;89(3):283-8.

PMID:16696409
Abstract

OBJECTIVES

To determine the prevalence of discordant twins in Siriraj Hospital and to evaluate associated factors.

DESIGN

Cross-sectional study.

SETTING

Department of Obstetrics and Gynecology, Faculty of Medicine Siriraj Hospital, Mahidol University.

SUBJECTS

A total of 150 women with twin pregnancy, > or = 28 weeks of gestation, who had deliveries of both live twins at Siriraj Hospital from 2003 to 2004.

METHOD

A review of medical records was conducted. Discordance was defined as > or = 20% difference in birth weight. Prevalence of discordance was calculated and associated risk factors were evaluated.

RESULTS

Discordance was found in 35 cases; therefore, the prevalence was 23.3%. No significant association was found between discordance and various factors, including maternal age, maternal complications, parity, pregnant by assisted reproduction, gestational age at first diagnosis, chorionicity. However, discordant twins delivered at earlier gestational age compared to concordant twins (34.9 +/- 3.2 and 36.2 +/- 2.4 weeks, p = 0.037). Infants of discordant pairs were more likely to be admitted to the NICU than those of concordant pairs (17.1% and 3.9%, p < 0.001, both larger and smaller infants). Other neonatal morbidities were not significantly different.

CONCLUSION

Discordance twin was found in 23.3% of the cases. No significant associated risk factor was found. Infants of discordant pairs were more likely to be admitted to the NICU than those of concordant pairs.

摘要

目的

确定诗里拉吉医院不一致性双胎的患病率,并评估相关因素。

设计

横断面研究。

地点

玛希隆大学诗里拉吉医院医学院妇产科。

研究对象

2003年至2004年在诗里拉吉医院分娩的150例双胎妊娠孕妇,孕周≥28周,且双胎均为活产。

方法

对病历进行回顾。不一致性定义为出生体重差异≥20%。计算不一致性的患病率,并评估相关危险因素。

结果

发现35例不一致性双胎;因此,患病率为23.3%。未发现不一致性与各种因素之间存在显著关联,这些因素包括产妇年龄、产妇并发症、产次、辅助生殖受孕、首次诊断时的孕周、绒毛膜性。然而,与一致性双胎相比,不一致性双胎的分娩孕周更早(34.9±3.2周和36.2±2.4周,p = 0.037)。不一致性双胎的婴儿比一致性双胎的婴儿更有可能入住新生儿重症监护病房(17.1%和3.9%,p < 0.001,无论是较大还是较小的婴儿)。其他新生儿疾病无显著差异。

结论

23.3%的病例中发现了不一致性双胎。未发现显著的相关危险因素。不一致性双胎的婴儿比一致性双胎的婴儿更有可能入住新生儿重症监护病房。

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