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一种使用钨酸镉光电二极管探测器的台式兆伏级扇形束CT。II. 图像性能评估。

A bench-top megavoltage fan-beam CT using CdWO4-photodiode detectors. II. Image performance evaluation.

作者信息

Monajemi T T, Tu D, Fallone B G, Rathee S

机构信息

Department of Medical Physics, Cross Cancer Institute, University of Alberta, 11560 University Avenue, Edmonton, Alberta, Canada.

出版信息

Med Phys. 2006 Apr;33(4):1090-100. doi: 10.1118/1.2181291.

Abstract

Megavoltage computed tomography (MVCT) is a potential imaging tool for positioning and dose delivery verification during image guided radiotherapy. The problem with many MVCT detectors, however, is their low detective quantum efficiency (DQE) which leads to poor low contrast resolution (LCR) and high image noise. This makes separating the tumors from the soft tissue background difficult. This manuscript describes the imaging performance of our bench-top MVCT scanner that uses an 80-element detector array consisting of CdWO4-photodiode elements with a DQE of 19% in 6 MV and 26% in Co60 beams [T. T. Monajemi, S. Steciw, B. G. Fallone, and S. Rathee, "Modelling scintillator-photodiodes as detectors for megavoltage CT," Med. Phys. 31, 1225-1234 (2004)] at zero frequency. The imaging experiments presented were carried out mainly in a Co60 teletherapy unit, while the beam hardening characteristics of the system were also presented for a 6 MV beam. During image evaluation, persistent ring artifacts, caused by air gaps at the ends of the eight-element detector blocks, were removed by using a calibration procedure. The measured contrast of a low contrast target with a 20 mm diameter was determined to be independent of dose, between 2.1 and 17 cGy. The measured LCR of a target with a nominal contrast of 2.8% was reduced from 2.3% to 1.2% when the contrast target diameter was reduced from 15 to 5 mm, using 17 cGy for imaging. The signal to noise ratio of this system is shown to be proportional to the square root of dose. Most importantly, a low contrast target with a diameter of 6 mm and a nominal contrast level of 1.5% is resolved with a radiation dose of 2.1 cGy in the Co60 beam. The spatial resolution in the Co60 beam is limited to one line pair per centimeter mainly due to the size of the Co60 source.

摘要

兆伏级计算机断层扫描(MVCT)是图像引导放射治疗期间用于定位和剂量传递验证的一种潜在成像工具。然而,许多MVCT探测器存在的问题是其探测量子效率(DQE)较低,这导致低对比度分辨率(LCR)较差且图像噪声较高。这使得将肿瘤与软组织背景区分开来变得困难。本手稿描述了我们台式MVCT扫描仪的成像性能,该扫描仪使用由CdWO4光电二极管元件组成的80元件探测器阵列,在6 MV时DQE为19%,在Co60射束中DQE为26%[T. T. Monajemi、S. Steciw、B. G. Fallone和S. Rathee,“将闪烁体-光电二极管建模为兆伏级CT的探测器”,《医学物理》31,1225 - 1234(2004)],在零频率下。所呈现的成像实验主要在Co60远距离治疗装置中进行,同时也给出了该系统对于6 MV射束的束硬化特性。在图像评估期间,通过使用校准程序消除了由八元件探测器模块端部的气隙引起的持续环形伪影。测量得出,直径为20 mm的低对比度目标的对比度在2.1至17 cGy之间与剂量无关。当使用17 cGy进行成像时,标称对比度为2.8%的目标的测量LCR在对比度目标直径从15 mm减小到5 mm时从2.3%降至1.2%。该系统的信噪比与剂量的平方根成正比。最重要的是,在Co60射束中,使用2.1 cGy的辐射剂量可分辨出直径为6 mm且标称对比度水平为1.5%的低对比度目标。Co60射束中的空间分辨率主要由于Co60源的尺寸限制为每厘米一线对。

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