Abid Naushad, Bhatti Maqsood, Azharuddin Muhammad, Islam Muhammad
Department of Medicine, Aga Khan University Hospital, Karachi.
J Pak Med Assoc. 2006 Mar;56(3):95-8.
To study the epidemiological features of septic arthritis in the adult population and to identify the risk factors for mortality in septic arthritis.
A five year reterospective study was performed on cases with septic arthritis admitted in our hospital between January 1999 and December 2004. Patients were identified according to ICD codes, 711.00. Data was recorded on a standardized data sheet and analyzed by SPSS 11.5 software.
A total of 116 patients were identified, 69 were male (59.5%) and 47 female (40.55%). Mean age of patients was 49.22 years. The most common presenting clinical features were joint swelling (99.1%) and fever (60.3%), Knee joint was the most common joint involved (65.5%) followed by hip (11.2%). Gram stains of synovial fluid was done in 67.2% of cases out of which 22.4% had positive stains. Staphylococcus aureus was the most common organism isolated from blood as well as synovial fluid (18.8%). Mean haemoglobin was 10.83gm/dl and 57.8% of patients had total leukocyte count less than 11,000/cumm. Platelet count was greater than 150,000/cumm in 90.5% patients. Hypertension, renal failure, chronic liver disease and elevated ESR were identified as some of the potential risk factors for higher mortality in a cohort with septic arthritis.
Septic arthritis is associated with significant morbidity and mortality. These results highlight the importance of obtaining cultures before starting any treatment.
研究成年人群中脓毒性关节炎的流行病学特征,并确定脓毒性关节炎患者死亡的危险因素。
对1999年1月至2004年12月期间我院收治的脓毒性关节炎病例进行了为期五年的回顾性研究。根据国际疾病分类代码711.00确定患者。数据记录在标准化数据表上,并使用SPSS 11.5软件进行分析。
共确定116例患者,其中男性69例(59.5%),女性47例(40.55%)。患者的平均年龄为49.22岁。最常见的临床表现为关节肿胀(99.1%)和发热(60.3%),膝关节是最常受累的关节(65.5%),其次是髋关节(11.2%)。67.2%的病例进行了滑膜液革兰氏染色,其中22.4%染色呈阳性。金黄色葡萄球菌是从血液和滑膜液中分离出的最常见病原体(18.8%)。平均血红蛋白为10.83g/dl,57.8%的患者白细胞总数低于11,000/立方毫米。90.5%的患者血小板计数大于150,000/立方毫米。高血压、肾衰竭、慢性肝病和血沉升高被确定为脓毒性关节炎队列中较高死亡率的一些潜在危险因素。
脓毒性关节炎与显著的发病率和死亡率相关。这些结果突出了在开始任何治疗前进行培养的重要性。