Zaragoza Oscar, McClelland Erin E, Telzak Andrew, Casadevall Arturo
Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
FEMS Yeast Res. 2006 Jun;6(4):662-6. doi: 10.1111/j.1567-1364.2006.00070.x.
Under certain conditions, India ink particles can penetrate the capsule of the opportunistic pathogen Cryptococcus neoformans. India ink penetration gave two distinct patterns, one as a ring in the middle of the capsule, and another as a double spot located at opposite poles of the cells. These spots were perpendicularly orientated to the bud. This pattern suggests the existence of a localized structure deep in the capsule that can accumulate large insoluble particles. Although the mechanisms responsible for the assemblage and maintenance of ring-like channels are not understood, their existence deep within the capsule implies a new level of complexity for this enigmatic structure.
在某些条件下，印度墨汁颗粒可穿透机会性致病病原体新型隐球菌的荚膜。印度墨汁穿透呈现出两种不同的模式，一种是在荚膜中间形成一个环，另一种是在细胞相对两极形成双斑点。这些斑点垂直于芽的方向。这种模式表明在荚膜深处存在一种可积累大的不溶性颗粒的局部结构。尽管负责环状通道组装和维持的机制尚不清楚，但它们在荚膜深处的存在意味着这个神秘结构具有新的复杂程度。
