Berger R
Hôpital Necker-Enfants-Malades, EMI 0210 Inserm, 149, rue de Sèvres, 75743 Paris cedex 15, France.
Pathol Biol (Paris). 2007 Feb;55(1):1-12. doi: 10.1016/j.patbio.2006.04.005. Epub 2006 May 11.
The correct enumeration of human chromosomes, only established in 1956, has marked the starting point of the modern cytogenetics. The introduction of banding techniques, then of in situ hybridization techniques, and now of genomic microarray technology allowed a dramatic development of cytogenetics of which the main applications to basic and medical research are evoked in this review.
人类染色体的正确计数直到1956年才得以确立，这标志着现代细胞遗传学的起点。显带技术的引入，随后是原位杂交技术，现在是基因组微阵列技术，使得细胞遗传学得到了巨大的发展，本文将阐述其在基础研究和医学研究中的主要应用。
