Corradi Domenico, Mormandi Francesca, Tanzi Giulia, Ricci Roberto, Bini Paola, Giuliotti Sara, Zompatori Maurizio
Section of Pathology, Department of Pathology and Laboratory Medicine, University of Parma, 43100 Parma, Italy.
Cardiovasc Pathol. 2006 May-Jun;15(3):157-60. doi: 10.1016/j.carpath.2006.02.003.
A fatal pulmonary tumor microembolism is rarely caused by an occult gastric cancer.
We report the case of a 40-year-old woman who died after 3 days of progressive dyspnea, cough, and pulmonary hypertension. Postmortem examination demonstrated the presence of an occult diffuse-type gastric carcinoma, which had caused emboli in about 80% of small pulmonary arteries and arterioles. Despite an interatrial defect in the fossa ovalis, no parenchymal metastases were documented.
Pulmonary tumor microembolism may be suspected in patients complaining of unexplained progressive dyspnea and who develop acute or subacute cor pulmonale.