隐匿性胃癌患者因肺肿瘤微栓塞导致的致命性肺心病
Fatal cor pulmonale caused by pulmonary tumor microembolism in a patient with occult gastric cancer.
作者信息
Corradi Domenico, Mormandi Francesca, Tanzi Giulia, Ricci Roberto, Bini Paola, Giuliotti Sara, Zompatori Maurizio
机构信息
Section of Pathology, Department of Pathology and Laboratory Medicine, University of Parma, 43100 Parma, Italy.
出版信息
Cardiovasc Pathol. 2006 May-Jun;15(3):157-60. doi: 10.1016/j.carpath.2006.02.003.
BACKGROUND
A fatal pulmonary tumor microembolism is rarely caused by an occult gastric cancer.
METHODS AND RESULTS
We report the case of a 40-year-old woman who died after 3 days of progressive dyspnea, cough, and pulmonary hypertension. Postmortem examination demonstrated the presence of an occult diffuse-type gastric carcinoma, which had caused emboli in about 80% of small pulmonary arteries and arterioles. Despite an interatrial defect in the fossa ovalis, no parenchymal metastases were documented.
CONCLUSION
Pulmonary tumor microembolism may be suspected in patients complaining of unexplained progressive dyspnea and who develop acute or subacute cor pulmonale.
背景
致命性肺肿瘤微栓塞很少由隐匿性胃癌引起。
方法与结果
我们报告一例40岁女性病例，该患者在出现进行性呼吸困难、咳嗽和肺动脉高压3天后死亡。尸检显示存在隐匿性弥漫型胃癌，其导致约80%的小肺动脉和小动脉出现栓子。尽管卵圆窝存在房间隔缺损，但未发现实质转移。
结论
对于主诉不明原因进行性呼吸困难且出现急性或亚急性肺心病的患者，可能怀疑存在肺肿瘤微栓塞。
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