Al-Suleiman S A, Al-Jama F E, Rahman J, Rahman M S
King Fahad Hospital, Al-Khobar, Saudi Arabia.
J Obstet Gynaecol. 2006 Apr;26(3):200-4. doi: 10.1080/01443610500508295.
The incidence of multiple pregnancies with more than two fetuses has significantly increased since the introduction of ovulation agents and assisted reproductive technologies. Over a 15-year period there were 35 triplet pregnancies beyond 24 weeks that delivered at the King Fahad Hospital, an incidence of 1 in 1,099 deliveries. Early diagnosis is important for improving the rate of fetal salvage in triplet pregnancy. These pregnancies were managed on an outpatient basis. Prophylactic interventions were not utilised. A total of 91% of the pregnancies had at least one antenatal complication, pre-term labour being the most common (80%) followed by anaemia (43%). The average gestational age at delivery was 31.7 weeks (SD 4.2 weeks). A total of 94.3% of the patients were delivered by lower segment caesarean section. The mean birth weight of the neonates was 1,552 g (SD 510 g) and mean 5-min Apgar score was 7.6 (SD 0.8). The corrected perinatal mortality rate in the study was 152/1,000. Pregnancy outcome did not vary with birth order or mode of conception. Higher rate of pre-term births among triplet pregnancies make considerable demands on the neonatal intensive care unit. All methods of assisted reproduction should aim at prevention of multifetal pregnancies.
自排卵药物和辅助生殖技术应用以来，怀有两个以上胎儿的多胎妊娠发生率显著增加。在15年期间，法赫德国王医院有35例孕24周以上的三胎妊娠分娩，发生率为1/1099次分娩。早期诊断对于提高三胎妊娠的胎儿挽救率很重要。这些妊娠在门诊进行管理。未采用预防性干预措施。共有91%的妊娠至少有一种产前并发症，早产最为常见（80%），其次是贫血（43%）。分娩时的平均孕周为31.7周（标准差4.2周）。共有94.3%的患者通过下段剖宫产分娩。新生儿的平均出生体重为1552克（标准差510克），5分钟Apgar评分平均为7.6（标准差0.8）。该研究中的校正围产儿死亡率为152/1000。妊娠结局不随出生顺序或受孕方式而变化。三胎妊娠中较高的早产率对新生儿重症监护病房提出了相当大的需求。所有辅助生殖方法都应旨在预防多胎妊娠。
