一种与布莱因维尔突吻鲸（Mesoplodon densirostris）生殖器病变相关的新型γ疱疹病毒。
A novel gammaherpesvirus associated with genital lesions in a Blainville's beaked whale (Mesoplodon densirostris).
作者信息
Saliki Jeremiah T, Cooper Emily J, Rotstein David S, Caseltine Shannon L, Pabst D Ann, McLellan William A, Govett Pamela, Harms Craig, Smolarek Kara A, Romero Carlos H
机构信息
Oklahoma Animal Disease Diagnostic Laboratory, College of Veterinary Medicine, Oklahoma State University, Stillwater, Oklahoma 74078, USA.
出版信息
J Wildl Dis. 2006 Jan;42(1):142-8. doi: 10.7589/0090-3558-42.1.142.
An adult male Blainville's beaked whale (Mesoplodon densirostris) was found stranded on the Atlantic coast of the USA on 28 January 2004. Necropsy revealed a focal papilloma-like penile lesion, the cells from which revealed single 4-6 microm basophilic intranuclear inclusions. Total DNA extracted from lesion material was tested using a pan-herpes-virus PCR assay that targets the DNA polymerase gene and found to be positive. When the amplified DNA fragment was cloned, sequenced, and compared to GenBank-deposited herpesvirus DNA polymerase sequences, the detected virus was determined to be a distinct member of the Gammaherpesvirinae subfamily of herpesviruses. This new virus, tentatively named Ziphiid herpesvirus type 1, was associated with but not determined to be the cause of genital disease in the Blainville's beaked whale.
2004年1月28日，一头成年雄性布兰氏喙鲸（Mesoplodon densirostris）在美国大西洋海岸被发现搁浅。尸检发现阴茎上有一个灶性乳头状瘤样病变，病变细胞显示有单个4 - 6微米的嗜碱性核内包涵体。使用针对DNA聚合酶基因的泛疱疹病毒PCR检测法对从病变材料中提取的总DNA进行检测，结果呈阳性。当对扩增的DNA片段进行克隆、测序并与GenBank中保存的疱疹病毒DNA聚合酶序列进行比较时，检测到的病毒被确定为疱疹病毒γ疱疹病毒亚科的一个独特成员。这种新病毒暂命名为布兰氏喙鲸疱疹病毒1型，与布兰氏喙鲸的生殖器疾病有关，但尚未确定其为病因。
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