Otoom S A, Sequeira R P
Department of Pharmacology and Therapeutics, Faculty of Medicine, Arabian Gulf University, Manama, Bahrain.
Int J Clin Pract. 2006 May;60(5):565-70. doi: 10.1111/j.1742-1241.2005.00808.x.
It is now evident that both developed and developing countries are experiencing many aspects of inappropriate use of drugs in their health care facilities. This is the first study in the region performed to examine the most common problems of irrational use of drugs and their causes in two Middle East countries--Jordan and Syria. Ninety senior participants from Jordan (50-15 physicians and 35 pharmacists) and Syria (40-12 physicians and 28 pharmacists) were enrolled in this study. The participants were asked to fill two questionnaires that deal with the problems and causes of irrational use of drugs in their country. Additionally, the participants were asked to perform a prescription analysis using WHO prescribing indicators on 40 prescriptions taken randomly from a comprehensive health centre in their country. The main drug use problems identified in the two countries were almost the same, but they vary in the percentage of occurrence and include excessive use of antibiotics and antidiarrhoeals, overprescribing of nonsteroidal anti-inflammatory drugs, prescribing by tradename, excessive use of antibiotics to treat minor upper respiratory infections and self-medication by the public. The main causes of irrational use of drugs were poor medical records, lack of patient education about illnesses and drugs, no family doctor system, lack of standard treatment guidelines and lack of continuing medical education for doctors and pharmacists. The results of this study are important for decision-makers to utilise when putting policies and strategies to improve the use of drugs in both countries.
现在很明显,发达国家和发展中国家的医疗保健机构都存在药物使用不当的诸多问题。这是该地区首次开展的一项研究,旨在调查中东两个国家——约旦和叙利亚——药物不合理使用的最常见问题及其成因。来自约旦(50名,其中15名医生和35名药剂师)和叙利亚(40名,其中12名医生和28名药剂师)的90名资深参与者参与了这项研究。参与者被要求填写两份问卷,内容涉及本国药物不合理使用的问题和成因。此外,还要求参与者使用世界卫生组织的处方指标,对从本国一家综合健康中心随机抽取的40份处方进行分析。两国确定的主要药物使用问题几乎相同,但出现的百分比有所不同,包括抗生素和止泻药的过度使用、非甾体抗炎药的过度处方、按商品名开药、用抗生素过度治疗轻度上呼吸道感染以及公众自我用药。药物不合理使用的主要原因包括医疗记录不完善、缺乏对患者的疾病和药物教育、没有家庭医生制度、缺乏标准治疗指南以及医生和药剂师缺乏继续医学教育。这项研究的结果对于两国决策者在制定改善药物使用的政策和战略时加以利用具有重要意义。