Namasivayam Saravanan, Kalra Mannudeep K, Small William C, Torres William E, Mittal Pardeep K
Department of Radiology, Division of Abdominal Imaging, Emory University Hospital and Emory University School of Medicine, Atlanta, GA 30322, USA.
Curr Probl Diagn Radiol. 2006 May-Jun;35(3):102-14. doi: 10.1067/j.cpradiol.2006.02.005.
Renal transplantation is the treatment of choice for end-stage renal disease. Living related kidney donation is the major source of renal grafts due to limited availability of cadaveric kidneys. Open nephrectomy was used to harvest donor kidneys. However, the laparoscopic approach is associated with less postoperative pain and quick recovery. So, most centers now prefer a laparoscopic approach to explant donor kidneys. Laparoscopic approach is technically challenging due to limited operative visibility. Hence, accurate preoperative detection of renal arterial and venous anomalies is imperative to avoid inadvertent vascular injury and bleeding. The preoperative workup of renal donors includes clinical evaluation, laboratory tests, and imaging. Traditionally, the renal donors were evaluated with conventional imaging techniques, which included renal catheter angiography and intravenous urography. However, conventional imaging is invasive, expensive, and less accurate for evaluation of complex renal venous anomalies, small calculi, and diffuse or focal renal parenchymal lesions. The introduction of multidetector row computed tomography (MDCT) revolutionized the CT technology by enabling isotropic resolution with faster scan coverage in a single, short breath-hold. Consequently, MDCT has now replaced conventional imaging for comprehensive imaging of potential living renal donors. MDCT is a minimally invasive technique that can accurately detect urolithiasis, renal arterial and venous anomalies, renal parenchymal lesions, and urinary tract anomalies. Renal vascular anomalies detected by MDCT can help the surgeon in planning donor nephrectomy. MDCT with three-dimensional CT angiography enables accurate preoperative renal vascular mapping. This article reviews the role of MDCT in preoperative evaluation of potential laparoscopic renal donors.
肾移植是终末期肾病的首选治疗方法。由于尸体肾来源有限,活体亲属肾捐赠是肾移植的主要来源。过去采用开放肾切除术获取供肾。然而,腹腔镜手术方式术后疼痛较轻且恢复较快。因此,现在大多数中心更倾向于采用腹腔镜方式摘取供肾。由于手术视野有限,腹腔镜手术在技术上具有挑战性。因此,术前准确检测肾动静脉异常对于避免意外血管损伤和出血至关重要。肾供体的术前检查包括临床评估、实验室检查和影像学检查。传统上,肾供体采用传统影像学技术进行评估,包括肾导管血管造影和静脉肾盂造影。然而,传统影像学检查具有侵入性、费用高,对于复杂肾静脉异常、小结石以及弥漫性或局灶性肾实质病变的评估准确性较低。多排螺旋计算机断层扫描(MDCT)的引入彻底改变了CT技术,它能够在单次短暂屏气时以更快的扫描覆盖范围实现各向同性分辨率。因此,MDCT现在已取代传统影像学检查,用于对潜在活体肾供体进行全面成像。MDCT是一种微创技术,能够准确检测尿路结石、肾动静脉异常、肾实质病变和尿路异常。MDCT检测到的肾血管异常有助于外科医生规划供肾切除术。带有三维CT血管造影的MDCT能够实现准确的术前肾血管成像。本文综述了MDCT在潜在腹腔镜肾供体术前评估中的作用。