Institute for Cell, Animal and Population Biology, University of Edinburgh, Kings Buildings, West Mains Road, Edinburgh, EH9 3JT UK.
Trends Ecol Evol. 2004 Feb;19(2):58-60. doi: 10.1016/j.tree.2003.11.011.
Invertebrates have an immune response that differs considerably from the acquired immune response found in vertebrates. However, new studies indicate that past experience with a pathogen can provide individual invertebrates, or their descendants, with enhanced immunity. This prophylactic effect, termed immunological priming, is functionally similar to the acquired immune response in vertebrates. This newfound complexity of invertebrate immunity begs investigation into the conditions under which immunological priming should evolve, and its consequences for population dynamics.
无脊椎动物的免疫反应与脊椎动物的获得性免疫反应有很大的不同。然而,新的研究表明,过去与病原体的接触可以为单个无脊椎动物或它们的后代提供增强的免疫力。这种预防效果被称为免疫启动,在功能上类似于脊椎动物的获得性免疫反应。无脊椎动物免疫的这种新复杂性使得人们有必要研究免疫启动应该在什么条件下进化,以及它对种群动态的影响。