Moore Heidi K, Mundt James C, Modell Jack G, Rodrigues Heidi E, DeBrota David J, Jefferson James J, Greist John H
Healthcare Technology Systems, Inc. Madison, WI 53717, USA.
J Clin Psychopharmacol. 2006 Jun;26(3):321-4. doi: 10.1097/01.jcp.0000219918.96434.4d.
This article presents descriptive and psychometric data from 26,168 Hamilton Depression Rating Scale (HAM-D) scores administered via Interactive Voice Response (IVR) in 17 randomized clinical trials sponsored by 6 pharmaceutical companies. To provide evidence for construct validity, the IVR HAM-D scores before and after randomization are compared, and the change in the IVR HAM-D scores over time after randomization are examined. In addition, the evidence for the reliability of the IVR-administered HAM-D is presented. An examination of the distribution of first-time IVR HAM-Ds before randomization may provide useful information to researchers planning to use the IVR HAM-D as a screening tool for entry or to verify baseline severity in randomized clinical trials.
本文展示了来自6家制药公司赞助的17项随机临床试验中，通过交互式语音应答（IVR）系统录入的26,168份汉密尔顿抑郁量表（HAM-D）评分的描述性和心理测量学数据。为提供结构效度的证据，对随机分组前后的IVR HAM-D评分进行了比较，并研究了随机分组后IVR HAM-D评分随时间的变化。此外，还展示了IVR方式 administered HAM-D的信度证据。对随机分组前首次IVR HAM-D评分的分布进行检查，可能会为计划在随机临床试验中使用IVR HAM-D作为入组筛选工具或验证基线严重程度的研究人员提供有用信息。
