光动力疗法治疗视网膜血管瘤样增生I期

Photodynamic therapy in retinal angiomatous proliferation stage I.

作者信息

Panagiotidis D, Karagiannis D A, Baltatzis S

机构信息

Department of Ophthalmology, Medical School of Athens University, Athens, Greece.

出版信息

Eur J Ophthalmol. 2006 Mar-Apr;16(2):326-9. doi: 10.1177/112067210601600221.

DOI:10.1177/112067210601600221

PMID:16703554

Abstract

PURPOSE

To report a case of photodynamic therapy (PDT) treatment in an 85-year-old patient with retinal angiomatous proliferation (RAP) stage I.

METHODS

According to Treatment of Age-Related Macular Degeneration with Photodynamic Therapy and Verteporfin in Photodynamic Therapy study guidelines, two sessions of PDT with verteporfin were performed, which was activated by a diode laser light at 690 nm.

RESULTS

The left eye was treated with PDT because of RAP stage I. Even in the early stage of RAP, PDT treatment did not alter the natural course of the disease. In particular, the lesion evolved towards stage III, being initially in stage I, with the final result of development of retinal pigment epithelial (RPE) tear after the second session of PDT treatment. CONCLUSIONS; Even in the early stage of RAP, PDT treatment did not alter the natural course of the disease, with the final result of RPE tear after the second session of PDT treatment.

摘要

目的

报告一例85岁视网膜血管瘤样增生（RAP）I期患者接受光动力疗法（PDT）治疗的病例。

方法

根据光动力疗法治疗年龄相关性黄斑变性及光动力疗法中维替泊芬的研究指南，使用维替泊芬进行了两次PDT治疗，由690nm的二极管激光激活。

结果

左眼因RAP I期接受了PDT治疗。即使在RAP的早期阶段，PDT治疗也未改变疾病的自然进程。特别是，病变最初处于I期，在接受第二次PDT治疗后发展为III期，并最终导致视网膜色素上皮（RPE）撕裂。结论：即使在RAP的早期阶段，PDT治疗也未改变疾病的自然进程，第二次PDT治疗的最终结果是RPE撕裂。