Suppr超能文献

何时合并假设并针对多重检验进行调整。

When to combine hypotheses and adjust for multiple tests.

作者信息

Veazie Peter J

机构信息

Department of Community and Preventive Medicine, University of Rochester, 601 Elmwood Ave., Box 644, Rochester, NY 14642, USA.

出版信息

Health Serv Res. 2006 Jun;41(3 Pt 1):804-18. doi: 10.1111/j.1475-6773.2006.00512.x.

Abstract

OBJECTIVE

To provide guidelines for identifying composite hypotheses and addressing the probability of false rejection for multiple hypotheses.

DATA SOURCES AND STUDY SETTING

Examples from the literature in health services research are used to motivate the discussion of composite hypothesis tests and multiple hypotheses.

METHODS

This article is a didactic presentation.

PRINCIPAL FINDINGS

It is not rare to find mistaken inferences in health services research because of inattention to appropriate hypothesis generation and multiple hypotheses testing. Guidelines are presented to help researchers identify composite hypotheses and set significance levels to account for multiple tests.

CONCLUSIONS

It is important for the quality of scholarship that inferences are valid: properly identifying composite hypotheses and accounting for multiple tests provides some assurance in this regard.

摘要

目的

为识别复合假设及解决多重假设的错误拒绝概率提供指导方针。

数据来源与研究背景

卫生服务研究文献中的实例用于推动对复合假设检验和多重假设的讨论。

方法

本文是一篇教学性论述。

主要发现

由于对适当的假设生成和多重假设检验关注不足,在卫生服务研究中发现错误推断并不罕见。本文提出了指导方针,以帮助研究人员识别复合假设并设定显著性水平,以应对多重检验。

结论

推理有效对于学术质量很重要:正确识别复合假设并考虑多重检验在这方面提供了一定保证。

相似文献

1
When to combine hypotheses and adjust for multiple tests.
Health Serv Res. 2006 Jun;41(3 Pt 1):804-18. doi: 10.1111/j.1475-6773.2006.00512.x.
3
Correlation and causation: a comment.
Perspect Biol Med. 2005 Winter;48(1 Suppl):S88-94.
4
Statistical and nonstatistical significance: implications for health care researchers.
Qual Manag Health Care. 2007 Apr-Jun;16(2):104-12. doi: 10.1097/01.QMH.0000267447.55500.57.
5
Qualitative research methods: key features and insights gained from use in infection prevention research.
Am J Infect Control. 2008 Dec;36(10):764-71. doi: 10.1016/j.ajic.2008.03.010. Epub 2008 Oct 3.
6
A hierarchy of evidence for assessing qualitative health research.
J Clin Epidemiol. 2007 Jan;60(1):43-9. doi: 10.1016/j.jclinepi.2006.03.014. Epub 2006 Sep 28.
7
The EQUATOR Network: promoting the transparent and accurate reporting of research.
Dev Med Child Neurol. 2008 Oct;50(10):723. doi: 10.1111/j.1469-8749.2008.03107.x.
8
A health researcher's guide to qualitative methodologies.
Aust N Z J Public Health. 2007 Oct;31(5):433-7. doi: 10.1111/j.1753-6405.2007.00114.x.
10
Attention should be given to multiplicity issues in systematic reviews.
J Clin Epidemiol. 2008 Sep;61(9):857-65. doi: 10.1016/j.jclinepi.2008.03.004.

引用本文的文献

1
Aggression as a contributing factor to social defeat and stress vulnerability.
Neurobiol Stress. 2025 Apr 23;36:100728. doi: 10.1016/j.ynstr.2025.100728. eCollection 2025 May.
2
Acute carbamoylated erythropoietin reduces social stress-induced anxiety and depression-related behaviors.
Neuropharmacology. 2025 Jun 11;278:110558. doi: 10.1016/j.neuropharm.2025.110558.
3
The Role of Five-Factor Model Personality Traits in a Web-Based Relationship Improvement Program.
Couple Family Psychol. 2024 Jun;13(2):117-133. doi: 10.1037/cfp0000221. Epub 2022 Apr 4.
5
Single administration of a psychedelic [(R)-DOI] influences coping strategies to an escapable social stress.
Neuropharmacology. 2024 Jul 1;252:109949. doi: 10.1016/j.neuropharm.2024.109949. Epub 2024 Apr 16.
6
Anxiolytic reversal of classically conditioned / chronic stress-induced gene expression and learning in the Stress Alternatives Model.
Behav Brain Res. 2023 Feb 25;440:114258. doi: 10.1016/j.bbr.2022.114258. Epub 2022 Dec 12.
7
Contextual generalization of social stress learning is modulated by orexin receptors in basolateral amygdala.
Neuropharmacology. 2022 Sep 1;215:109168. doi: 10.1016/j.neuropharm.2022.109168. Epub 2022 Jun 17.
10
Effects of white Gaussian noise on dynamic balance in healthy young adults.
Sci Rep. 2021 Mar 9;11(1):5455. doi: 10.1038/s41598-021-84706-8.

本文引用的文献

1
Describing data requires no adjustment for multiple comparisons: a reply from Savitz and Olshan.
Am J Epidemiol. 1998 May 1;147(9):813-4; discussion 815. doi: 10.1093/oxfordjournals.aje.a009532.
2
Multiple comparisons, explained.
Am J Epidemiol. 1998 May 1;147(9):807-12; discussion 815. doi: 10.1093/oxfordjournals.aje.a009531.
3
Invited commentary: Re: "Multiple comparisons and related issues in the interpretation of epidemiologic data".
Am J Epidemiol. 1998 May 1;147(9):801-6. doi: 10.1093/oxfordjournals.aje.a009530.
4
Multiple comparisons and related issues in the interpretation of epidemiologic data.
Am J Epidemiol. 1995 Nov 1;142(9):904-8. doi: 10.1093/oxfordjournals.aje.a117737.
5

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验