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碳纳米管及相关复合材料的生物医学应用研究与开发

[Research and development of biomedical application of carbon nanotubes and related composites].

作者信息

Guo Xiaotian, Xu Haiyan

机构信息

Institute of Basic Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100005, China.

出版信息

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2006 Apr;23(2):438-41.

PMID:16706384
Abstract

Carbon nanotubes, a new member of the carbon material family, can be considered as graphite sheets rolled-up into cylinders with diameters ranging in the nanometer scale. In recent years, carbon nanotubes have attracted intensive interests because of their unique nanostructures and outstanding mechanical, electrical and magnetic properties. In this paper, the structures and basic features of carbon nanotubes were described in brief. The research advances in the carbon nanotubes on the specific recognition of biomolecules by surface modification and functionalization, in the enhancement to cell growth as culture scaffolds in vitro, and in the improvement of biocompatibility for implantable biomedical material were reviewed. Also comments were made on their potential applications in biomedical sensor and biomedical microelectrics.

摘要

碳纳米管是碳材料家族的新成员,可被视为由直径在纳米尺度范围内的石墨片卷曲而成的圆柱体。近年来,碳纳米管因其独特的纳米结构以及出色的机械、电学和磁学性能而引起了广泛关注。本文简要描述了碳纳米管的结构和基本特征。综述了碳纳米管通过表面修饰和功能化对生物分子进行特异性识别、作为体外培养支架促进细胞生长以及改善可植入生物医学材料生物相容性方面的研究进展。此外,还对其在生物医学传感器和生物医学微电子学中的潜在应用进行了评述。

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1
[Research and development of biomedical application of carbon nanotubes and related composites].碳纳米管及相关复合材料的生物医学应用研究与开发
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2006 Apr;23(2):438-41.
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Carbon nanotube applications for tissue engineering.用于组织工程的碳纳米管应用。
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Using single-walled carbon nanotubes nonwoven films as scaffolds to enhance long-term cell proliferation in vitro.使用单壁碳纳米管非织造膜作为支架以增强体外长期细胞增殖。
J Biomed Mater Res A. 2006 Nov;79(2):298-306. doi: 10.1002/jbm.a.30787.
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Carbon nanotubes in scaffolds for tissue engineering.用于组织工程的支架中的碳纳米管。
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Chemically functionalized carbon nanotubes.化学功能化碳纳米管
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Carbon nanotubes for biomedical applications.用于生物医学应用的碳纳米管。
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Chapter 6 - Carbon nanotubes as substrates/scaffolds for neural cell growth.第六章 - 碳纳米管作为神经细胞生长的基底/支架。
Prog Brain Res. 2009;180:110-25. doi: 10.1016/S0079-6123(08)80006-4. Epub 2009 Dec 8.
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The carbon nanocosmos: novel materials for the twenty-first century.碳纳米世界:21世纪的新型材料。
Philos Trans A Math Phys Eng Sci. 2003 Dec 15;361(1813):2789-806. doi: 10.1098/rsta.2003.1262.
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Mechanisms of pulmonary toxicity and medical applications of carbon nanotubes: Two faces of Janus?碳纳米管的肺毒性机制及医学应用:双面雅努斯?
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Current investigations into carbon nanotubes for biomedical application.当前对用于生物医学应用的碳纳米管的研究。
Biomed Mater. 2010 Apr;5(2):22001. doi: 10.1088/1748-6041/5/2/022001. Epub 2010 Mar 25.

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[Research progress on application of carbon nanotubes in bone tissue engineering scaffold].碳纳米管在骨组织工程支架中的应用研究进展
Zhejiang Da Xue Xue Bao Yi Xue Ban. 2016 Mar;45(2):161-9. doi: 10.3785/j.issn.1008-9292.2016.03.09.