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下颌前伸与阻塞性睡眠呼吸暂停:一种确定有效下颌前突的方法。

Mandibular advancement and obstructive sleep apnoea: a method for determining effective mandibular protrusion.

作者信息

Dort L C, Hadjuk E, Remmers J E

机构信息

Dept of Surgery, University of Calgary, AB, Canada.

出版信息

Eur Respir J. 2006 May;27(5):1003-9. doi: 10.1183/09031936.06.00077804.

Abstract

The objectives of the study were to test the hypotheses that it is possible, during routine polysomnography (PSG), to prospectively identify favourable candidates for mandibular repositioning appliance (MRA) therapy in the treatment of obstructive sleep apnoea (OSA) and to accurately estimate an optimal protrusive distance at which to fabricate the MRA. A series of subjects underwent a remotely controlled mandibular positioner (RCMP) test during PSG monitoring. The ability of the RCMP test to eliminate OSA and the target protrusion at which that occurred was compared with the success of a custom oral MRA in the 33 subjects who completed the protocol. The RCMP test was a success in 15 subjects and a failure in 18 subjects. Appliance therapy was initiated in 38 subjects and completed in 33. MRA therapy was successful at target protrusion in 80% of subjects who had a successful RCMP test and failed in 78% of those who failed the RCMP test. In conclusion the remotely controlled mandibular positioner test outcome demonstrated a statistically significant association with mandibular repositioning appliance outcome. The target protrusion determined during the remotely controlled mandibular positioner test was the effective therapeutic protrusion in subjects with a successful remotely controlled mandibular positioner test.

摘要

本研究的目的是检验以下假设

在常规多导睡眠图(PSG)检查期间,可以前瞻性地识别出阻塞性睡眠呼吸暂停(OSA)患者中适合下颌重新定位矫治器(MRA)治疗的有利候选者,并准确估计制作MRA时的最佳前伸距离。一系列受试者在PSG监测期间接受了遥控下颌定位器(RCMP)测试。将RCMP测试消除OSA的能力以及发生消除时的目标前伸距离与33名完成该方案的受试者中定制口腔MRA的成功情况进行了比较。RCMP测试在15名受试者中成功,在18名受试者中失败。38名受试者开始了矫治器治疗,33名完成了治疗。在RCMP测试成功的受试者中,80%的受试者在目标前伸距离时MRA治疗成功,而在RCMP测试失败的受试者中,78%的受试者治疗失败。总之,遥控下颌定位器测试结果与下颌重新定位矫治器结果在统计学上具有显著相关性。在遥控下颌定位器测试期间确定的目标前伸距离是遥控下颌定位器测试成功的受试者的有效治疗前伸距离。

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