Suppr超能文献

一种替代人体测量特征作为心血管疾病风险因素的有效性:来自下肢创伤性截肢个体的实例

Validity of an alternative anthropometric trait as cardiovascular diseases risk factor: example from individuals with traumatic lower extremity amputation.

作者信息

Mozumdar A, Roy S K

机构信息

Biological Anthropology Unit, Indian Statistical Institute, Kolkata, West Bengal, India.

出版信息

Eur J Clin Nutr. 2006 Oct;60(10):1180-8. doi: 10.1038/sj.ejcn.1602434. Epub 2006 May 17.

Abstract

BACKGROUND

Published studies reveal that individuals with lower extremity amputation are vulnerable to cardiovascular diseases (CVD) because of poor physical activity level. Many cardiovascular risk assessment studies have utilized anthropometric traits (primarily body mass index and waist circumference) as cardiovascular risk factor. However, some studies emphasized the technical limitations of measuring waist circumference for studying cardiovascular risk, and so it is difficult to obtain correct measurement from the individuals with lower extremity amputation.

OBJECTIVES

The objectives of the present article are to study the prevalence of CVD risk factors among the individuals with traumatic lower extremity amputation and to test the validity of upper arm circumference (UAC) as an alternative anthropometric measurement for screening the CVD risk condition.

SUBJECTS AND SETTING

Anthropometric data and other cardiovascular traits data have been collected from unilateral traumatic lower extremity amputated adult males (n = 85) residing in Calcutta and adjoining areas.

RESULTS

Results show higher prevalence of cardiovascular risk factor among individuals with above-knee amputation than below-knee amputation. The receiver operating characteristics curve analysis shows significant ability of upper arm circumference to diagnose cardiovascular risk condition. The cutoff value of UAC > 26.6 cm show maximum sensitivity and specificity for the diagnosis of cardiovascular risk condition. Although, binomial tests for equality of proportion does not show any significant difference, however, agreement statistics reveal better diagnostic ability of cutoff value of UAC than the existing cutoff value of waist circumference.

CONCLUSIONS

Therefore, UAC provides a better assessment of cardiovascular risk condition than does waist circumference especially for individuals with lower extremity amputation.

SPONSORSHIP

Indian Statistical Institute, Kolkata.

摘要

背景

已发表的研究表明,由于身体活动水平较低,下肢截肢个体易患心血管疾病(CVD)。许多心血管风险评估研究将人体测量特征(主要是体重指数和腰围)用作心血管危险因素。然而,一些研究强调了测量腰围以研究心血管风险的技术局限性,因此很难从下肢截肢个体获得正确的测量值。

目的

本文的目的是研究创伤性下肢截肢个体中CVD危险因素的患病率,并测试上臂围(UAC)作为筛查CVD风险状况的替代人体测量方法的有效性。

对象与地点

已收集居住在加尔各答及其周边地区的单侧创伤性下肢截肢成年男性(n = 85)的人体测量数据和其他心血管特征数据。

结果

结果显示,膝上截肢个体的心血管危险因素患病率高于膝下截肢个体。受试者工作特征曲线分析表明,上臂围对诊断心血管风险状况具有显著能力。UAC>26.6 cm的临界值对心血管风险状况的诊断具有最大的敏感性和特异性。虽然比例相等的二项式检验未显示任何显著差异,但一致性统计显示,UAC临界值的诊断能力优于现有的腰围临界值。

结论

因此,与腰围相比,UAC能更好地评估心血管风险状况,尤其是对下肢截肢个体。

资助

印度统计研究所,加尔各答。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验