Mozumdar A, Roy S K
Biological Anthropology Unit, Indian Statistical Institute, Kolkata, West Bengal, India.
Eur J Clin Nutr. 2006 Oct;60(10):1180-8. doi: 10.1038/sj.ejcn.1602434. Epub 2006 May 17.
Published studies reveal that individuals with lower extremity amputation are vulnerable to cardiovascular diseases (CVD) because of poor physical activity level. Many cardiovascular risk assessment studies have utilized anthropometric traits (primarily body mass index and waist circumference) as cardiovascular risk factor. However, some studies emphasized the technical limitations of measuring waist circumference for studying cardiovascular risk, and so it is difficult to obtain correct measurement from the individuals with lower extremity amputation.
The objectives of the present article are to study the prevalence of CVD risk factors among the individuals with traumatic lower extremity amputation and to test the validity of upper arm circumference (UAC) as an alternative anthropometric measurement for screening the CVD risk condition.
Anthropometric data and other cardiovascular traits data have been collected from unilateral traumatic lower extremity amputated adult males (n = 85) residing in Calcutta and adjoining areas.
Results show higher prevalence of cardiovascular risk factor among individuals with above-knee amputation than below-knee amputation. The receiver operating characteristics curve analysis shows significant ability of upper arm circumference to diagnose cardiovascular risk condition. The cutoff value of UAC > 26.6 cm show maximum sensitivity and specificity for the diagnosis of cardiovascular risk condition. Although, binomial tests for equality of proportion does not show any significant difference, however, agreement statistics reveal better diagnostic ability of cutoff value of UAC than the existing cutoff value of waist circumference.
Therefore, UAC provides a better assessment of cardiovascular risk condition than does waist circumference especially for individuals with lower extremity amputation.
Indian Statistical Institute, Kolkata.
已发表的研究表明,由于身体活动水平较低,下肢截肢个体易患心血管疾病(CVD)。许多心血管风险评估研究将人体测量特征(主要是体重指数和腰围)用作心血管危险因素。然而,一些研究强调了测量腰围以研究心血管风险的技术局限性,因此很难从下肢截肢个体获得正确的测量值。
本文的目的是研究创伤性下肢截肢个体中CVD危险因素的患病率,并测试上臂围(UAC)作为筛查CVD风险状况的替代人体测量方法的有效性。
已收集居住在加尔各答及其周边地区的单侧创伤性下肢截肢成年男性(n = 85)的人体测量数据和其他心血管特征数据。
结果显示,膝上截肢个体的心血管危险因素患病率高于膝下截肢个体。受试者工作特征曲线分析表明,上臂围对诊断心血管风险状况具有显著能力。UAC>26.6 cm的临界值对心血管风险状况的诊断具有最大的敏感性和特异性。虽然比例相等的二项式检验未显示任何显著差异,但一致性统计显示,UAC临界值的诊断能力优于现有的腰围临界值。
因此,与腰围相比,UAC能更好地评估心血管风险状况,尤其是对下肢截肢个体。
印度统计研究所,加尔各答。