Moon Kyung-Sub, Jung Shin, Lee Jae-Hyuk, Jung Tae-Young, Kim In-young, Kim Soo-Han, Kang Sam-Suk
Department of Neurosurgery, Chonnam National University Research Institute of Medical Sciences, Chonnam National University Hwasun Hospital and Medical School, Gwangju, South Korea.
Neuropathology. 2006 Apr;26(2):141-6. doi: 10.1111/j.1440-1789.2006.00643.x.
We present a case of benign osteoblastoma of the occipital bone. Benign osteoblastoma is an uncommon primary bone tumor, which usually involves the vertebrae and the long bones. This tumor rarely develops in the calvaria, showing a preference for the temporal and frontal bones when it does. To the best of our knowledge, this case is only the eighth reported case of benign osteoblastoma confined to the occipital bone. A 20-year-old male presented with a mild tender mass lesion of the occipital area, just below the lambda. Plain X-ray films and CT scans demonstrated an osteolytic mass surrounded by the sclerotic rim within the diploic space. MRI proved to be effective for the evaluation of the intracranial and intraosseous extensions of the tumor. However, it was very difficult to formulate a differential diagnosis against other osteoblastic tumors, or osteoid osteoma, in view of its radiological appearance. The final diagnosis was obtained by careful consideration of the histopathological characteristics of the tumor combined with its clinical and radiological features. Although generally regarded as benign, a complete resection is preferred over conventional curettage as this can guard against possible recurrence and malignant transformation.
我们报告一例枕骨良性骨母细胞瘤病例。良性骨母细胞瘤是一种罕见的原发性骨肿瘤,通常累及脊椎和长骨。这种肿瘤很少发生在颅盖骨,若发生则多倾向于颞骨和额骨。据我们所知,该病例是第八例报告的局限于枕骨的良性骨母细胞瘤。一名20岁男性,在枕区(人字缝下方)出现一个轻度压痛的肿块病变。X线平片和CT扫描显示在板障间隙内有一个被硬化边缘包绕的溶骨性肿块。MRI被证明对评估肿瘤的颅内和骨内扩展有效。然而,鉴于其影像学表现,很难与其他成骨肿瘤或骨样骨瘤进行鉴别诊断。通过仔细考虑肿瘤的组织病理学特征并结合其临床和影像学特征得出最终诊断。尽管通常认为是良性的,但与传统刮除术相比,更倾向于完整切除,因为这样可以防止可能的复发和恶变。