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颅颈坏死性筋膜炎的手术清创:时机窗口

Surgical debridement of craniocervical necrotizing fasciitis: the window of opportunity.

作者信息

Hanna B C, Delap T G, Scott K, Sinclair S

机构信息

Department of ENT, Antrim Area Hospital, Antrim, Northern Ireland, UK.

出版信息

J Laryngol Otol. 2006 Aug;120(8):702-4. doi: 10.1017/S0022215106001447. Epub 2006 May 19.

Abstract

Craniocervical necrotizing fasciitis (CCNF) has a potentially high morbidity and mortality. Late presentation, shock and disseminated intravascular coagulation are associated with a particularly poor prognosis. Early recognition and aggressive treatment is advised. A case report is presented of a late presentation of necrotizing fasciitis of the face, neck and anterior thoracic wall. Despite adverse prognostic indicators, surgical debridement was performed. Intensive medical treatment included continuous renal replacement therapy and intravenous immunoglobulin. Survival in this case illustrates that the window of opportunity for surgically treating CCNF extends to the advanced stages of the disease, albeit with increased morbidity.

摘要

颅颈坏死性筋膜炎(CCNF)具有潜在的高发病率和死亡率。就诊延迟、休克和弥散性血管内凝血与特别差的预后相关。建议早期识别并积极治疗。本文报告了一例面部、颈部和前胸壁坏死性筋膜炎就诊延迟的病例。尽管存在不良预后指标,但仍进行了手术清创。强化药物治疗包括持续肾脏替代治疗和静脉注射免疫球蛋白。该病例的存活表明,手术治疗CCNF的机会窗口可延伸至疾病晚期,尽管发病率会增加。

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