Röckmann Heike, Feller Gabriele, Schadendorf Dirk, Goerdt Sergij
Department of Dermatology, Venereology and Allergology, University Medical Center Mannheim, Ruprecht-Karls-Universität Heidelberg, Germany.
Eur J Dermatol. 2006 May-Jun;16(3):302-6.
We describe a 42-year-old woman who had erythemateous plaques with sharply demarcated margins and fine scaling on her right trunk and leg. The lesions had a linear distribution following the lines of Blaschko. Histological findings supported the diagnosis of subacute cutaneous lupus erythematosus (SCLE) on the lines of Blaschko. Treatment with systemic corticosteroids and anti-malarial agents resulted in remission. Up to now, eighteen cases of linear lupus erythematosus have been described. Linear lupus erythematosus mostly affects children presenting with lesions on the scalp that were classified as discoid lupus erythematosus. To our knowledge, this is the first case of subacute cutaneous lupus erythematosus on the lines of Blaschko.
我们描述了一位42岁的女性,其右躯干和腿部出现边界清晰的红斑性斑块,并伴有细小鳞屑。这些皮损沿Blaschko线呈线状分布。组织学检查结果支持沿Blaschko线分布的亚急性皮肤型红斑狼疮(SCLE)的诊断。全身使用皮质类固醇和抗疟药治疗后病情缓解。到目前为止,已有18例线状红斑狼疮的病例被报道。线状红斑狼疮主要影响儿童,皮损多位于头皮,曾被归类为盘状红斑狼疮。据我们所知,这是首例沿Blaschko线分布的亚急性皮肤型红斑狼疮病例。