Bae Hae-Gyung, Sung Heungsup, Kim Mi-Na, Lee Eun-Jung, Koo Lee Sung
Department of Laboratory Medicine, Asan Medical Center and University of Ulsan College of Medicine, Seoul, Korea.
Scand J Infect Dis. 2006;38(5):383-6. doi: 10.1080/00365540500372945.
We report the first clinical isolate of linezolid- and vancomycin-resistant Enterococcus faecium (VREF) in Korea. The minimum inhibitory concentration of linezolid was in direct proportion to the number of copies of the G2576U mutation according to sequencing and restriction fragment length polymorphism analysis of the 23S rRNA gene.
我们报道了韩国首例耐利奈唑胺和万古霉素的屎肠球菌(VREF)临床分离株。根据23S rRNA基因的测序和限制性片段长度多态性分析,利奈唑胺的最低抑菌浓度与G2576U突变的拷贝数成正比。