被仙台病毒持续感染的BHK细胞在小鼠体内诱导干扰素产生。
Iterferon induction in mice by BHK cells persistently infected with HVJ.
作者信息
Ito Y, Nisiyama Y, Shimokata K, Kimura Y, Nagata I
出版信息
J Gen Virol. 1975 Apr;27(1):93-5. doi: 10.1099/0022-1317-27-1-93.
PMID:167109
Abstract
Intraperitoneal injection into mice of BHK-HVJ cells (BHK cells persistently infected with HVJ) induced considerable amounts of circulating interferon. Sonication of BHK-HVJ cells almost totally abolished their interferon inducing capacities. This result suggests that a certain native organized structure of virus infected cells might be essential for production of interferon in this system, as is suggested in the in vitro sytem.
摘要
将BHK-HVJ细胞（持续感染HVJ的BHK细胞）腹腔注射到小鼠体内可诱导产生大量循环干扰素。对BHK-HVJ细胞进行超声处理几乎完全消除了它们的干扰素诱导能力。这一结果表明，病毒感染细胞的某种天然组织结构可能对于该系统中干扰素的产生至关重要，正如体外系统中所提示的那样。
Zotero 插件