Sahney Shobha, Chinnock Richard
Department of Pediatrics, Loma Linda University Children's Hospital, Loma Linda, CA 92350, USA.
Pediatr Transplant. 2006 Jun;10(4):408-12. doi: 10.1111/j.1399-3046.2005.00484.x.
Most infants and children referred for cardiac transplantation have low cardiac output with concurrent renal hypoperfusion leading to renal insufficiency and failure. This article is a review of the literature of and a single center's experience with combined heart and kidney failure in infants and children less than 10 yr of age. While 39 infants less than 10 yr of age were dialyzed pre- or peri-operatively, none required dialysis support at the time of discharge or in 5-10 yr follow-up. Based on our experience we recommend heart transplant alone in infants and young children with primary heart disease even though they have renal dysfunction.
大多数接受心脏移植评估的婴幼儿心输出量低，同时存在肾灌注不足，导致肾功能不全和肾衰竭。本文回顾了相关文献，并介绍了一个单中心对10岁以下婴幼儿合并心力衰竭和肾衰竭的治疗经验。虽然有39名10岁以下的婴幼儿在术前或术中接受了透析，但出院时或5至10年随访期间均无需透析支持。根据我们的经验，我们建议患有原发性心脏病的婴幼儿即使存在肾功能障碍，也仅进行心脏移植。
