Kojima Naoki, Ishida Jyunnrou, Inagawa Hiroshi, Okada Yasusei, Machida Michirou, Terada Taizou
Department of Intensive Care and Emergency Medicine, Showa General Hospital.
Chudoku Kenkyu. 2006 Apr;19(2):141-6.
A 32-yr-old woman with acute gastritis and migraine used Naron commonly (the principal ingredients are acetaminophen and bromvalerylurea) and had been taking about 3g of acetaminophen daily for several days before admission. She was hospitalized with severe diffuse abdominal pain. On physical examination she had a peritoneal sign and laboratory studies showed elevated liver enzymes, hypophosphatemia, hypokalemia and low blood urea nitrogen(BUN). Serum acetaminophen level was 5.5 microg/mL on admission, so she seemed to be suffered from not only single ingestion but also repeated overdosing. Although we needed for aggressive phosphate and potassium repletion for about a week, all symptoms were distinguished after she quitted acetaminophen ingestion. In addition to hepatic dysfunction, renal failure and disseminated intravascular coagulopathy, we should pay attention to various symptoms like in this case when treating for a acetaminophen poisoning.
一名32岁患有急性胃炎和偏头痛的女性经常使用Naron（主要成分是对乙酰氨基酚和溴戊酰脲），入院前几天每天服用约3克对乙酰氨基酚。她因严重的弥漫性腹痛住院。体格检查时有腹膜刺激征，实验室检查显示肝酶升高、低磷血症、低钾血症和低血尿素氮（BUN）。入院时血清对乙酰氨基酚水平为5.5微克/毫升，所以她似乎不仅是单次过量服用，而且是反复过量服药。尽管我们需要积极补充磷酸盐和钾约一周时间，但在她停止服用对乙酰氨基酚后所有症状都消失了。在治疗对乙酰氨基酚中毒时，除了肝功能障碍、肾衰竭和弥散性血管内凝血外，我们还应注意像这种病例中的各种症状。
