Costa Rogério A, Skaf Mirian, Melo Luiz A S, Calucci Daniela, Cardillo Jose A, Castro Jarbas C, Huang David, Wojtkowski Maciej
U.D.A.T.-Retina Diagnostic and Treatment Division, Hospital de Olhos de Araraquara, Rua Padre Duarte 989 ap 172, Araraquara, SP 14801 310, Brazil.
Prog Retin Eye Res. 2006 May;25(3):325-53. doi: 10.1016/j.preteyeres.2006.03.001. Epub 2006 May 22.
Over the 15 years since the original description, optical coherence tomography (OCT) has become one of the key diagnostic technologies in the ophthalmic subspecialty areas of retinal diseases and glaucoma. The reason for the widespread adoption of this technology originates from at least two properties of the OCT results: on the one hand, the results are accessible to the non-specialist where microscopic retinal abnormalities are grossly and easily noticeable; on the other hand, results are reproducible and exceedingly quantitative in the hands of the specialist. However, as in any other imaging technique in ophthalmology, some artifacts are expected to occur. Understanding of the basic principles of image acquisition and data processing as well as recognition of OCT limitations are crucial issues to using this equipment with cleverness. Herein, we took a brief look in the past of OCT and have explained the key basic physical principles of this imaging technology. In addition, each of the several steps encompassing a third generation OCT evaluation of retinal tissues has been addressed in details. A comprehensive explanation about next generation OCT systems has also been provided and, to conclude, we have commented on the future directions of this exceptional technique.
自最初被描述以来的15年里，光学相干断层扫描（OCT）已成为视网膜疾病和青光眼等眼科亚专业领域的关键诊断技术之一。这项技术被广泛采用的原因至少源于OCT结果的两个特性：一方面，非专业人员也能看懂结果，其中视网膜微观异常清晰易见；另一方面，在专业人员手中，结果具有可重复性且极为定量。然而，与眼科的任何其他成像技术一样，预计会出现一些伪像。了解图像采集和数据处理的基本原理以及认识到OCT的局限性是明智使用该设备的关键问题。在此，我们简要回顾了OCT的发展历程，并解释了这项成像技术的关键基本物理原理。此外，还详细阐述了对视网膜组织进行第三代OCT评估所涉及的几个步骤。还提供了关于下一代OCT系统的全面解释，最后，我们对这项卓越技术的未来发展方向进行了评论。
